Context: Although many studies have investigated the molecular mechanisms underlying
hypoxia-related cardiomyocyte damage, the role of necrosis in cardiomyocyte death …

Diabetic mellitus (DM) portends poor prognosis concerning pressure overloaded heart
disease. Branched-chain amino acids (BCAAs), elements of essential amino acids, have …

The objective of this study was to examine whether genetically determined differences in the
guanylyl cyclase/natriuretic peptide receptor-A gene (Npr1) affect cardiac expression of …

Ferroptosis is a nonapoptotic form of regulated cell death that has been reported to play a
central role in cardiac ischemia‒reperfusion (I/R) injury. N-acetyltransferase 10 (NAT10) …

Cardiomyocytes apoptosis following reperfusion injury causes irreversible damage to
cardiac function. Understanding the mechanisms underlying cardiomyocytes death under …

Myocardial ischemia/hypoxia-reperfusion injury mediates the progression of multiple
cardiovascular diseases. It has been reported that knockdown of adaptor protein containing …

Background Ischemia/reperfusion-mediated myocardial infarction (MIRI) is a major
pathological factor implicated in the progression of ischemic heart disease, but the key …

Background: C1q/tumor necrosis factor-related protein 3 (CTRP3) has been reported to be a
crucial regulator in myocardial infarction. Nevertheless, the potential molecular mechanism …

Prolonged cardiac overexpression of the mitochondrial biogenesis regulatory transcriptional
coactivator PGC-1α disrupts cardiac contractile function and its genetic ablation limits …

Tuberculosis (TB) is a zoonotic infectious disease caused by Mycobacterium tuberculosis
(Mtb). Apoptosis and necrosis caused by the interaction between the host and the pathogen …