Background Lysine-specific histone demethylase 3A (KDM3A) is a potent histone modifier
that is frequently implicated in the progression of several malignancies. However, its role in …

As an important 5‑methylcytidine (m 5 C) methyltransferase, NOP2/Sun RNA
methyltransferase family member 6 (NSUN6) has been reported to play an important role in …

Objective: Osteosarcoma (OS) is a common bone cancer that usually influences children.
Metastasis and recurrence are the main reasons for the poor prognosis. In this study, we …

Osteosarcoma (OS) is a prevalent primary bone sarcoma. Methyltransferase-like 3
(METTL3) is dysregulated in human malignancies. This study explored the mechanism of …

N6-methyladenosine modification is the most common RNA modification mechanism in
mammals. YTHDF1, a m6A reader, can recognize the m6A of mRNAs to facilitate the …

Abnormal RNA m6A methylation is known to lead to the occurrence and progression of
multiple cancers including gastric cancer (GC). However, the integrative effects of all m6A …

Purpose N6-methyladenosine (m6A) is the most abundant internal modification on
eukaryotic mRNA and gained increasing attention recently. More and more evidence …

Osteosarcoma is recognized as a malignant tumor in the skeletal system. Long non‐coding
RNAs (lncRNAs) have been exhibited to play crucial roles in osteosarcoma development …

Osteosarcoma (OS) is characterized by rapid growth and early metastasis. However, its
mechanism remains unclear. N 6-methyladenosine (m 6 A) modification and its regulatory …

Abstract Aberrant N6-methyladenosine (m6A) modification of mRNAs contributes
significantly to the epigenetic tumorigenesis, however, its precise role and the key targets in …