N6‐methyladenosine reader YTHDF3 regulates melanoma metastasis via its 'executor'LOXL3
H Shi, J Xiong, L Gan, Y Zhang, C Zhang… - Clinical and …, 2022 - Wiley Online Library
Background A number of studies have demonstrated that N6‐methyladenosine (m6A) plays
a vital role in the pathological process of various tumours. Recently, it was found that m6A …
a vital role in the pathological process of various tumours. Recently, it was found that m6A …
[HTML][HTML] N6-methyladenosine modified LINC00901 promotes pancreatic cancer progression through IGF2BP2/MYC axis
WX Peng, F Liu, JH Jiang, H Yuan, Z Zhang, L Yang… - Genes & diseases, 2023 - Elsevier
Accumulating evidence indicates that RNA methylation at N 6-methyladenosine (m6A) plays
an important regulatory role in gene expression and aberrant mRNA m6A modification is …
an important regulatory role in gene expression and aberrant mRNA m6A modification is …
[HTML][HTML] An integrative analysis of DNA methylation in osteosarcoma
J Xu, D Li, Z Cai, Y Zhang, Y Huang, B Su… - Journal of bone oncology, 2017 - Elsevier
Background The study aimed to analyze aberrantly methylated genes, relevant pathways
and transcription factors (TFs) in osteosarcoma (OS) development. Methods Based on the …
and transcription factors (TFs) in osteosarcoma (OS) development. Methods Based on the …
KLF4 functions as an oncogene in promoting cancer stem cell-like characteristics in osteosarcoma cells
X Qi, Y Li, Y Zhang, T Xu, B Lu, L Fang, J Gao… - Acta Pharmacologica …, 2019 - nature.com
Despite more effective chemotherapy combined with limb-salvage surgery for the
osteosarcoma treatment, survival rates for osteosarcoma patients have stagnated over the …
osteosarcoma treatment, survival rates for osteosarcoma patients have stagnated over the …
FTO promotes proliferation and migration of bladder cancer via enhancing stability of STAT3 mRNA in an m6A-dependent manner
Z Sun, X Sun, G Qin, Y Li, G Zhou, X Jiang - Epigenetics, 2023 - Taylor & Francis
ABSTRACT N6-Methyladenosine (m6A) plays a key role in the occurrence and development
of various cancers. Fat mass and obesity‐associated protein (FTO) was is involved in …
of various cancers. Fat mass and obesity‐associated protein (FTO) was is involved in …
[HTML][HTML] YTHDF2 exerts tumor-suppressor roles in gastric cancer via up-regulating PPP2CA independently of m6A modification
Y Zhou, K Fan, N Dou, L Li, J Wang, J Chen… - Biological procedures …, 2023 - Springer
Background YTHDF2 is one of important readers of N6-methyladenosine (m6A) modification
on RNA. Growing evidence implicates that YTHDF2 takes an indispensable part in the …
on RNA. Growing evidence implicates that YTHDF2 takes an indispensable part in the …
m6A demethylase FTO facilitates tumor progression in lung squamous cell carcinoma by regulating MZF1 expression
J Liu, D Ren, Z Du, H Wang, H Zhang, Y Jin - Biochemical and biophysical …, 2018 - Elsevier
Abstract N 6-Methyladenosine (m 6 A) represents the most prevalent internal modification in
mammalian mRNAs. Emerging evidences suggest that m 6 A modification is profoundly …
mammalian mRNAs. Emerging evidences suggest that m 6 A modification is profoundly …
RNA demethylase ALKBH5 promotes ovarian carcinogenesis in a simulated tumour microenvironment through stimulating NF‐κB pathway
Y Jiang, Y Wan, M Gong, S Zhou, J Qiu… - Journal of cellular …, 2020 - Wiley Online Library
Methylation is the main form of RNA modification. N6‐methyladenine (m6A) regulates the
splicing and translation of mRNA. Alk B homologue 5 (ALKBH5) participates in the biological …
splicing and translation of mRNA. Alk B homologue 5 (ALKBH5) participates in the biological …
[HTML][HTML] YTHDF2 mediates the mRNA degradation of the tumor suppressors to induce AKT phosphorylation in N6-methyladenosine-dependent way in prostate cancer
J Li, H Xie, Y Ying, H Chen, H Yan, L He, M Xu, X Xu… - Molecular cancer, 2020 - Springer
Abstract Background N6-methyladenosine (m 6 A) is the most abundant modification in
mRNA of humans. Emerging evidence has supported the fact that m 6 A is comprehensively …
mRNA of humans. Emerging evidence has supported the fact that m 6 A is comprehensively …
[HTML][HTML] Identification of the role and clinical prognostic value of target genes of m6A RNA methylation regulators in glioma
P Cong, T Wu, X Huang, H Liang, X Gao… - Frontiers in Cell and …, 2021 - frontiersin.org
m6A RNA methylation regulators can regulate the growth, progression, and invasion of
glioma cells by regulating their target genes, which provides a reliable support for the m6A …
glioma cells by regulating their target genes, which provides a reliable support for the m6A …