[HTML][HTML] m6A methyltransferase KIAA1429 accelerates oral squamous cell carcinoma via regulating glycolysis and ferroptosis
K Xu, X Dai, J Yue - Translational Oncology, 2023 - Elsevier
Abstract N 6-methyladenosine (m 6 A) modification acts as the most prevalent modification
on eukaryotic RNA, and its function on oral squamous cell carcinoma (OSCC) is still unclear …
on eukaryotic RNA, and its function on oral squamous cell carcinoma (OSCC) is still unclear …
The m6A Reader YTHDF1 Facilitates the Tumorigenesis and Metastasis of Gastric Cancer via USP14 Translation in an m6A-Dependent Manner
XY Chen, R Liang, YC Yi, HN Fan, M Chen… - Frontiers in cell and …, 2021 - frontiersin.org
Objectives N6-methyladenosine (m6A) RNA methylation is implicated in the progression of
multiple cancers via influencing mRNA modification. YTHDF1 can act as an oncogene in …
multiple cancers via influencing mRNA modification. YTHDF1 can act as an oncogene in …
m6A demethylase FTO promotes tumor progression via regulation of lipid metabolism in esophageal cancer
X Duan, L Yang, L Wang, Q Liu, K Zhang, S Liu, C Liu… - Cell & bioscience, 2022 - Springer
Background Epitranscriptomics studies have contributed greatly to the development of
research on human cancers. In recent years, N6-methyladenosine (m6A), an RNA …
research on human cancers. In recent years, N6-methyladenosine (m6A), an RNA …
Downregulation of KLF13 through DNMT1-mediated hypermethylation promotes glioma cell proliferation and invasion
R Wu, Q Yun, J Zhang, J Bao - OncoTargets and therapy, 2019 - Taylor & Francis
Background Recent evidence indicates that Kruppel-like factor 13 (KLF13) has critical roles
in regulating cell differentiation, proliferation and may function as a tumor suppressor …
in regulating cell differentiation, proliferation and may function as a tumor suppressor …
METTL3 facilitates oral squamous cell carcinoma tumorigenesis by enhancing c-Myc stability via YTHDF1-mediated m6A modification
W Zhao, Y Cui, L Liu, X Ma, X Qi, Y Wang, Z Liu… - … Therapy-Nucleic Acids, 2020 - cell.com
N 6-Methyladenosine (m 6 A) is the most common internal modification of eukaryotic
messenger RNA (mRNA) that occurred on the N 6 nitrogen of adenosine. However, the roles …
messenger RNA (mRNA) that occurred on the N 6 nitrogen of adenosine. However, the roles …
[HTML][HTML] The m6A methyltransferase METTL3-mediated N6-methyladenosine modification of DEK mRNA to promote gastric cancer cell growth and metastasis
HM Zhang, FF Qi, J Wang, YY Duan, LL Zhao… - International Journal of …, 2022 - mdpi.com
Gastric cancer (GC) is the fifth most common cancer and the third deadliest cancer in the
world, and the occurrence and development of GC are influenced by epigenetics …
world, and the occurrence and development of GC are influenced by epigenetics …
ALKBH5 prevents hepatocellular carcinoma progression by post-transcriptional inhibition of PAQR4 in an m6A dependent manner
W Wang, Q Huang, Z Liao, H Zhang, Y Liu, F Liu… - … Hematology & Oncology, 2023 - Springer
Abstract Background N6-methyladenosine (m6A) is a prevalent modification of mRNA and is
known to play important roles in tumorigenesis in many types of cancer. The function of N6 …
known to play important roles in tumorigenesis in many types of cancer. The function of N6 …
N6-methyladenosine modification-related long non-coding RNAs are potential biomarkers for predicting the prognosis of patients with osteosarcoma
K Yang, F Wang, K Li, G Peng, H Yang… - … in Cancer Research …, 2022 - journals.sagepub.com
Background: The role of N6-methyladenosine (m6A)-related long non-coding RNAs
(lncRNAs) in osteosarcoma (OS) has not been fully studied yet. We aimed to identify m6A …
(lncRNAs) in osteosarcoma (OS) has not been fully studied yet. We aimed to identify m6A …
FTO mediated ERBB2 demethylation promotes tumor progression in esophageal squamous cell carcinoma cells
F Zhao, F Ge, M Xie, Z Li, C Zang, L Kong, Y Pu… - Clinical & Experimental …, 2022 - Springer
Abstract N6-methyladenosine (m6A) is the most prevalent and internal modification that
occurs in the messenger RNAs of eukaryotes. However, knowledge of the impact of these …
occurs in the messenger RNAs of eukaryotes. However, knowledge of the impact of these …
[HTML][HTML] Methylation of kruppel-like factor 2 (KLF2) associates with its expression and non-small cell lung cancer progression
W Jiang, X Xu, S Deng, J Luo, H Xu… - American Journal of …, 2017 - ncbi.nlm.nih.gov
Abstract Kruppel-like factor 2 (KLF2) is a putative tumor suppressor gene. This study
investigated its role and epigenetic mechanisms in human non-small cell lung cancer …
investigated its role and epigenetic mechanisms in human non-small cell lung cancer …