The m6A Reader YTHDF1 Facilitates the Tumorigenesis and Metastasis of Gastric Cancer via USP14 Translation in an m6A-Dependent Manner
XY Chen, R Liang, YC Yi, HN Fan, M Chen… - Frontiers in cell and …, 2021 - frontiersin.org
Objectives N6-methyladenosine (m6A) RNA methylation is implicated in the progression of
multiple cancers via influencing mRNA modification. YTHDF1 can act as an oncogene in …
multiple cancers via influencing mRNA modification. YTHDF1 can act as an oncogene in …
METTL3 facilitates oral squamous cell carcinoma tumorigenesis by enhancing c-Myc stability via YTHDF1-mediated m6A modification
W Zhao, Y Cui, L Liu, X Ma, X Qi, Y Wang, Z Liu… - … Therapy-Nucleic Acids, 2020 - cell.com
N 6-Methyladenosine (m 6 A) is the most common internal modification of eukaryotic
messenger RNA (mRNA) that occurred on the N 6 nitrogen of adenosine. However, the roles …
messenger RNA (mRNA) that occurred on the N 6 nitrogen of adenosine. However, the roles …
m6A regulators are associated with osteosarcoma metastasis and have prognostic significance: a study based on public databases
W Zhang, L Wang, P Zhang, Q Zhang - Medicine, 2021 - journals.lww.com
Background: Osteosarcoma represents the most common malignant bone tumor with high
metastatic potential and inferior prognosis. RNA methylation (N6-methyladenosine [m6A]) is …
metastatic potential and inferior prognosis. RNA methylation (N6-methyladenosine [m6A]) is …
LINC00659 cooperated with ALKBH5 to accelerate gastric cancer progression by stabilising JAK1 mRNA in an m6A‐YTHDF2‐dependent manner
Abstract Background N6‐methyladenosine (m6A) RNA modification is known as a common
epigenetic regulation form in eukaryotic cells. Emerging studies show that m6A in noncoding …
epigenetic regulation form in eukaryotic cells. Emerging studies show that m6A in noncoding …
[HTML][HTML] ALKBH5 regulates IGF1R expression to promote the proliferation and tumorigenicity of endometrial cancer
X Pu, Z Gu, Z Gu - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Abstract N6-methyladenosine (m 6 A) messenger RNA methylation play important role in
cell proliferation and tumorigenicity of endometrial cancer, but the key mechanism is not fully …
cell proliferation and tumorigenicity of endometrial cancer, but the key mechanism is not fully …
[HTML][HTML] Methylation of kruppel-like factor 2 (KLF2) associates with its expression and non-small cell lung cancer progression
W Jiang, X Xu, S Deng, J Luo, H Xu… - American Journal of …, 2017 - ncbi.nlm.nih.gov
Abstract Kruppel-like factor 2 (KLF2) is a putative tumor suppressor gene. This study
investigated its role and epigenetic mechanisms in human non-small cell lung cancer …
investigated its role and epigenetic mechanisms in human non-small cell lung cancer …
N6-methyladenosine modification-related long non-coding RNAs are potential biomarkers for predicting the prognosis of patients with osteosarcoma
K Yang, F Wang, K Li, G Peng, H Yang… - … in Cancer Research …, 2022 - journals.sagepub.com
Background: The role of N6-methyladenosine (m6A)-related long non-coding RNAs
(lncRNAs) in osteosarcoma (OS) has not been fully studied yet. We aimed to identify m6A …
(lncRNAs) in osteosarcoma (OS) has not been fully studied yet. We aimed to identify m6A …
RNA N6‐methyladenosine methyltransferase‐like 3 promotes liver cancer progression through YTHDF2‐dependent posttranscriptional silencing of SOCS2
Epigenetic alterations have contributed greatly to human carcinogenesis. Conventional
epigenetic studies have predominantly focused on DNA methylation, histone modifications …
epigenetic studies have predominantly focused on DNA methylation, histone modifications …
Downregulation of KLF13 through DNMT1-mediated hypermethylation promotes glioma cell proliferation and invasion
R Wu, Q Yun, J Zhang, J Bao - OncoTargets and therapy, 2019 - Taylor & Francis
Background Recent evidence indicates that Kruppel-like factor 13 (KLF13) has critical roles
in regulating cell differentiation, proliferation and may function as a tumor suppressor …
in regulating cell differentiation, proliferation and may function as a tumor suppressor …
[PDF][PDF] RETRACTED: YTHDF1 facilitates the progression of hepatocellular carcinoma by promoting FZD5 mRNA translation in an m6A-dependent manner
X Liu, J Qin, T Gao, C Li, B He, B Pan, X Xu… - … Therapy-Nucleic Acids, 2020 - cell.com
Hepatocellular carcinoma (HCC), one of the most aggressive malignancies, ranks as the
fourth leading cause of cancerrelated deaths worldwide. Emerging evidence indicates that …
fourth leading cause of cancerrelated deaths worldwide. Emerging evidence indicates that …