[HTML][HTML] Long noncoding RNAs in key cellular processes involved in aortic aneurysms

Z Wu, M Trenner, RA Boon, JM Spin, L Maegdefessel - Atherosclerosis, 2020 - Elsevier
Aortic aneurysm (AA) is a complex and dangerous vascular disease, featuring progressive
and irreversible vessel dilatation. AA is typically detected either by screening, or identified …

Non coding RNAs in aortic aneurysmal disease

A Duggirala, F Delogu, TG Angelini, T Smith… - Frontiers in …, 2015 - frontiersin.org
An aneurysm is a local dilatation of a vessel wall which is> 50% its original diameter. Within
the spectrum of cardiovascular diseases, aortic aneurysms are among the most challenging …

Role of noncoding RNAs in the pathogenesis of abdominal aortic aneurysm: possible therapeutic targets?

S Kumar, RA Boon, L Maegdefessel… - Circulation …, 2019 - Am Heart Assoc
Abdominal aortic aneurysm (AAA) is a local dilatation of the abdominal aortic vessel wall
and is among the most challenging cardiovascular diseases as without urgent surgical …

MicroRNAs: novel players in aortic aneurysm

X Fu, Y Zhou, Z Cheng, X Liao… - BioMed research …, 2015 - Wiley Online Library
An aortic aneurysm (AA) is a common disease with potentially life‐threatening
complications. Despite significant improvements in the diagnosis and treatment of AA, the …

Micro-RNAs in abdominal aortic aneurysms: insights from animal models and relevance to human disease

J Raffort, F Lareyre, M Clement… - Cardiovascular …, 2016 - academic.oup.com
Abdominal aortic aneurysm (AAA) is a major health concern and may be associated with
high rates of mortality linked to acute complications. Diagnosis and treatment are …

The role of long non-coding RNA in abdominal aortic aneurysm

Y Xu, S Yang, G Xue - Frontiers in Genetics, 2023 - frontiersin.org
The abdominal aortic aneurysm (AAA) is characterized by segmental expansion of the
abdominal aorta and a high mortality rate. The characteristics of AAA suggest that apoptosis …

Non-coding RNA contribution to thoracic and abdominal aortic aneurysm disease development and progression

Y Li, L Maegdefessel - Frontiers in physiology, 2017 - frontiersin.org
Multiple research groups have started to uncover the complex genetic and epigenetic
machinery necessary to maintain cardiovascular homeostasis. In particular, the key …

The function of long non-coding RNAs in vascular biology and disease

FO Kok, AH Baker - Vascular pharmacology, 2019 - Elsevier
In recent years, it has been revealed that majority of the genome is transcribed in a cell-and
context-specific manner into a vast array of RNA transcripts that do not encode proteins …

Micromanaging abdominal aortic aneurysms

L Maegdefessel, JM Spin, M Adam, U Raaz… - International journal of …, 2013 - mdpi.com
The contribution of abdominal aortic aneurysm (AAA) disease to human morbidity and
mortality has increased in the aging, industrialized world. In response, extraordinary efforts …

MicroRNAs in abdominal aortic aneurysm

M Adam, U Raaz, JM Spin… - Current Vascular …, 2015 - ingentaconnect.com
Abdominal aortic aneurysms (AAA) are an important source of morbidity and mortality in the
US and worldwide. Treatment options are limited, with open surgery or endovascular repair …