The non-nucleoside reverse transcriptase inhibitors (NNRTIs) directly inhibit the HIV-1
reverse transcriptase (RT) by binding in a reversible and non-competitive manner to the …

The non-nucleoside reverse transcriptase inhibitors (NNRTIs) are a potent class of drugs,
which act by inhibiting HIV-1 reverse transcriptase. Although chemically diverse, all bind to a …

It is almost 20 years since NNRTIs were identified as a new class of antiretroviral drugs for
the treatment of HIV-1 infection. Although they belong to different and diverse chemical …

Three non‐nucleoside reverse transcriptase inhibitors (NNRTIs) are currently available for
treatment of HIV‐1 as part of combination antiretroviral therapy. Oral dosing is administered …

Various non-nucleoside reverse transcriptase inhibitors (NNRTIs) have been reported to
specifically inhibit human immunodeficiency virus type 1 (HIV-1): for example …

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are a diverse group of compounds
that induce allosteric changes in the human immunodeficiency virus type 1 (HIV-1) reverse …

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are promising drugs for the
treatment of HIV when used in combination with other anti-HIV drugs such as nucleoside …

Two classes of anti-HIV drugs are currently marketed which target the HIV-1 reverse
transcriptase (RT). The first explored class was the nucleoside RT inhibitors (NRTIs), such …

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) have, in addition to the nucleoside
reverse transcriptase inhibitors (NRTIs) and protease inhibitors (PIs), gained a definitive …

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are potent but limited tools in the
suppression of HIV. Nevirapine has shown efficacy in combination with other reverse …