Metallodrugs in cancer therapy: past, present and new strategies

I Kostova - Frontiers in Chemistry, 2024 - frontiersin.org
Cancer diagnostics and therapy that include metal-based pharmaceuticals have improved
over the past decades. The therapeutic importance and application of metals and their …

[图书][B] Metal-based anticancer agents

A Casini, A Vessières, SM Meier-Menches - 2019 - books.google.com
Metal-based anticancer drugs are among the most successful therapeutic agents, as
evidenced by the frequent prescription of selected platinum and arsenic compounds to …

Editorial [Hot topic: Metal-Containing Drugs and Novel Coordination Complexes in Therapeutic Anticancer Applications-Part II (Guest Editor: Irena Kostova)]

I Kostova - Anti-Cancer Agents in Medicinal Chemistry …, 2010 - ingentaconnect.com
While cancer remains a major killer in the developed world, a broad spectrum of novel and
exciting approaches are being developed and tested. The importance of metal compounds …

Emerging Trends in Metal‐based Anticancer Agents: Drug Design to Clinical Trials and their Mechanism of Action

A Temesgen, HC Ananda Murthy, AZ Enyew… - …, 2023 - Wiley Online Library
Metal‐based therapeutic strategies have been effectively used to treat a number of diseases
since the ancient period. However, the issue that emerged at this time was the indistinct …

[HTML][HTML] A review on metal complexes and its anti-cancer activities: Recent updates from in vivo studies

S Adhikari, P Nath, A Das, A Datta, N Baildya… - Biomedicine & …, 2024 - Elsevier
Research into cancer therapeutics has uncovered various potential medications based on
metal-containing scaffolds after the discovery and clinical applications of cisplatin as an anti …

Riding the metal wave: A review of the latest developments in metal-based anticancer agents

S Abdolmaleki, A Aliabadi, S Khaksar - Coordination Chemistry Reviews, 2024 - Elsevier
Metal-based complexes have demonstrated significant anticancer effects and have emerged
as candidates with great potential for cancer therapy. These agents are effective in a variety …

Recent advances of metal-based anticancer agents and their in vivo potential against various types of malignancies

P Nath, A Datta, S Adhikari - Handbook of animal models and its uses in …, 2022 - Springer
Metal-based complexes have tremendous capacity to interact with biological molecules and
modify their actions. Due to their ability to modify enzymatic action, metabolism and …

Metals in medicine

Z Liu, C Hartinger, N Kulak - Frontiers in Chemistry, 2022 - frontiersin.org
The field of metal-based pharmaceuticals (metallodrugs) is one of the main research areas
in bioinorganic chemistry. Metallodrugs have drawn great attention for their value as …

Metals in cancer research: Beyond platinum metallodrugs

A Casini, A Pöthig - ACS Central Science, 2024 - ACS Publications
The discovery of the medicinal properties of platinum complexes has fueled the design and
synthesis of new anticancer metallodrugs endowed with unique modes of action (MoA) …

Scope of organometallic compounds based on transition metal-arene systems as anticancer agents: starting from the classical paradigm to targeting multiple …

M Zaki, S Hairat, ES Aazam - RSC advances, 2019 - pubs.rsc.org
The advent of the clinically approved drug cisplatin started a new era in the design of
metallodrugs for cancer chemotherapy. However, to date, there has not been much success …