Complex disease genetics has been revolutionised in recent years by the advent of genome- wide association (GWA) studies. The chronic inflammatory bowel diseases (IBDs), Crohn's …
Inflammatory bowel disease, including Crohn's disease (CD) and ulcerative colitis (UC), and type 1 diabetes (T1D) are autoimmune diseases that may share common susceptibility …
WE Ek, M D'Amato, J Halfvarson - Annals of gastroenterology …, 2014 - ncbi.nlm.nih.gov
The influence of genetics in the etiology of inflammatory bowel disease (IBD) was initially demonstrated by epidemiological data, including differences in prevalence among different …
JH Cho, SR Brant - Gastroenterology, 2011 - Elsevier
Inflammatory bowel diseases (IBDs) are complex, multifactorial disorders that comprise Crohn's disease (CD) and ulcerative colitis (UC). Genome-wide association studies have …
WTC Uniken Venema, MD Voskuil… - The Journal of …, 2017 - Wiley Online Library
Recent studies have greatly improved our insight into the genetic background of inflammatory bowel disease (IBD). New high‐throughput technologies and large‐scale …
M Zhao, J Burisch - Digestive diseases and sciences, 2019 - Springer
Crohn's disease and ulcerative colitis constitute two major subgroups of inflammatory bowel diseases (IBD), a group of complex polygenic diseases characterized by chronic and …
N Younis, R Zarif, R Mahfouz - Molecular biology reports, 2020 - Springer
Inflammatory bowel disease (IBD) is a chronic relapsing inflammatory disease that can involve any part of the gastrointestinal tract. It includes two main disorders: Crohn's disease …
WY Mak, M Zhao, SC Ng… - Journal of gastroenterology …, 2020 - Wiley Online Library
The incidence of inflammatory bowel diseases (IBD) in East has risen over the past decade to become a global disease. The increasing number of studies on the incidence and course …
To further resolve the genetic architecture of the inflammatory bowel diseases ulcerative colitis and Crohn's disease, we sequenced the whole genomes of 4,280 patients at low …