Genome‐wide association studies of bipolar disorder: A systematic review of recent findings and their clinical implications

M Ikeda, T Saito, K Kondo… - Psychiatry and clinical …, 2018 - Wiley Online Library
Recent advances in molecular genetics have enabled assessments of the associations
among genetic variants (eg, single‐nucleotide polymorphisms) and susceptibility for …

Meta‐analysis of genetic association studies on bipolar disorder

F Seifuddin, PB Mahon, J Judy… - American Journal of …, 2012 - Wiley Online Library
Numerous candidate gene association studies of bipolar disorder (BP) have been carried
out, but the results have been inconsistent. Individual studies are typically underpowered to …

Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder

DT Chen, X Jiang, N Akula, YY Shugart… - Molecular …, 2013 - nature.com
Meta-analyses of bipolar disorder (BD) genome-wide association studies (GWAS) have
identified several genome-wide significant signals in European-ancestry samples, but so far …

Phenotypes, mechanisms and therapeutics: insights from bipolar disorder GWAS findings

M Li, T Li, X Xiao, J Chen, Z Hu, Y Fang - Molecular Psychiatry, 2022 - nature.com
Genome-wide association studies (GWAS) have reported substantial genomic loci
significantly associated with clinical risk of bipolar disorder (BD), and studies combining …

Genome-wide association study of bipolar disorder in European American and African American individuals

EN Smith, CS Bloss, JA Badner, T Barrett… - Molecular …, 2009 - nature.com
To identify bipolar disorder (BD) genetic susceptibility factors, we conducted two genome-
wide association (GWA) studies: one involving a sample of individuals of European ancestry …

Identification of pathways for bipolar disorder: a meta-analysis

JI Nurnberger, DL Koller, J Jung, HJ Edenberg… - JAMA …, 2014 - jamanetwork.com
Importance Genome-wide investigations provide systematic information regarding the
neurobiology of psychiatric disorders. Objective To identify biological pathways that …

Genetics of bipolar disorder: successful start to a long journey

N Craddock, P Sklar - Trends in Genetics, 2009 - cell.com
Family and twin studies attest to the importance of genetic factors influencing susceptibility to
bipolar disorder and to its genetic and phenotypic complexity. Although linkage and …

Genetics of bipolar disorder

B Kerner - The application of clinical genetics, 2014 - Taylor & Francis
Bipolar disorder is a common, complex genetic disorder, but the mode of transmission
remains to be discovered. Many researchers assume that common genomic variants carry …

Evidence for single nucleotide polymorphisms and their association with bipolar disorder

A Szczepankiewicz - Neuropsychiatric disease and treatment, 2013 - Taylor & Francis
Bipolar disorder (BD) is a complex disorder with a number of susceptibility genes and
environmental risk factors involved in its pathogenesis. In recent years, huge progress has …

The genetics of bipolar disorder

FJA Gordovez, FJ McMahon - Molecular psychiatry, 2020 - nature.com
Bipolar disorder (BD) is one of the most heritable mental illnesses, but the elucidation of its
genetic basis has proven to be a very challenging endeavor. Genome-Wide Association …