In silico evaluation and feasibility of near margin-less head and neck daily adaptive radiotherapy

M Dohopolski, J Visak, B Choi, B Meng… - Radiotherapy and …, 2024 - Elsevier
Objective We explore the potential dosimetric benefits of reducing treatment volumes
through daily adaptive radiation therapy for head and neck cancer (HNC) patients using the …

Dosimetric impact of simulated daily adaptive radiotherapy with significantly reduced setup margins in the definitive treatment of head and neck cancer

M Dohopolski, B Choi, B Meng, J Visak… - International Journal of …, 2022 - redjournal.org
Purpose/Objective (s) Even when treating head and neck cancer (HNC) with daily image-
guided radiation therapy, setup margins of 3-5 mm are required to ensure adequate …

Dosimetric evaluation of incorporating patient geometric variations into adaptive plan optimization through probabilistic treatment planning in head and neck cancers

Q Liu, J Liang, D Zhou, DJ Krauss, PY Chen… - International Journal of …, 2018 - Elsevier
Purpose Four-dimensional (4D) adaptive radiation therapy (ART) treatment planning is an
alternative to the conventional margin-based treatment planning approach. In 4D ART …

Real world clinical experience using daily intelligence-assisted online adaptive radiotherapy for head and neck cancer

P Blumenfeld, E Arbit, R Den, A Salhab… - Radiation …, 2024 - Springer
Background Adaptive radiation therapy (ART) offers a dynamic approach to address
structural and spatial changes that occur during radiotherapy (RT) for locally advanced head …

Head and neck margin reduction with adaptive radiation therapy: robustness of treatment plans against anatomy changes

S van Kranen, O Hamming-Vrieze, A Wolf… - International Journal of …, 2016 - Elsevier
Purpose We set out to investigate loss of target coverage from anatomy changes in head
and neck cancer patients as a function of applied safety margins and to verify a cone beam …

[HTML][HTML] Does adaptive radiotherapy for head and neck cancer favorably impact dosimetric, clinical, and toxicity outcomes?: A review

F Simopoulou, G Kyrgias, I Georgakopoulos… - Medicine, 2024 - journals.lww.com
Purpose: The current review aims to summarize the international experience of the impact of
adaptive radiotherapy on dosimetry and clinical and toxicity outcomes. Additionally, it might …

Clinical Experience With an Offline Adaptive Radiation Therapy Head and Neck Program: Dosimetric Benefits and Opportunities for Patient Selection

M Aristophanous, E Aliotta, P Lichtenwalner… - International Journal of …, 2024 - Elsevier
Purpose The objective of this study was to develop a linear accelerator (LINAC)-based
adaptive radiation therapy (ART) workflow for the head and neck that is informed by …

Incorporating uncertainty bounds in daily deformable dose accumulation for adaptive radiation therapy of head‐and‐neck cancer

JA García‐Alvarez, H Zhong, CJ Schultz, XA Li… - Medical …, 2023 - Wiley Online Library
Background The widespread use of deformable dose accumulation (DDA) in adaptive
radiotherapy (ART) has been limited due to the lack of clinically compatible methods to …

Expected treatment dose construction and adaptive inverse planning optimization: implementation for offline head and neck cancer adaptive radiotherapy

D Yan, J Liang - Medical Physics, 2013 - Wiley Online Library
Purpose: To construct expected treatment dose for adaptive inverse planning optimization,
and evaluate it on head and neck (h&n) cancer adaptive treatment modification. Methods …

Impact of manual contour editing on plan quality for online adaptive radiotherapy for head and neck cancer

S Wang, CY Liao, B Choi, S All, T Bai, J Visak… - Practical Radiation …, 2024 - Elsevier
Purpose Online adaptive radiotherapy (oART) has high resource costs especially for head-
and-neck (H&N) cancer, which requires recontouring complex targets and numerous organs …