Early first trimester peripheral blood cell microRNA predicts risk of preterm delivery in pregnant women: Proof of concept

EE Winger, JL Reed, X Ji - PLoS One, 2017 - journals.plos.org
Objective We investigated the capacity of first trimester peripheral blood mononuclear cell
(PBMC) microRNA to determine risk of spontaneous preterm birth among pregnant women …

MicroRNAs isolated from peripheral blood in the first trimester predict spontaneous preterm birth

EE Winger, JL Reed, X Ji, N Gomez-Lopez, P Pacora… - PLoS …, 2020 - journals.plos.org
Objective To predict spontaneous preterm birth among pregnant women in an African
American population using first trimester peripheral blood maternal immune cell microRNA …

First trimester PBMC microRNA predicts adverse pregnancy outcome

EE Winger, JL Reed, X Ji - American journal of reproductive …, 2014 - Wiley Online Library
Problem Prior to the end of the first trimester, pathogenic mechanisms may commit
pregnancies to adverse outcome such as pre‐eclampsia and miscarriage. A long‐term …

Peripheral blood cell microRNA quantification during the first trimester predicts preeclampsia: Proof of concept

EE Winger, JL Reed, X Ji, K Nicolaides - PLoS One, 2018 - journals.plos.org
Objective We investigated the capacity of microRNAs isolated from peripheral blood buffy
coat collected late during the first trimester to predict preeclampsia. Study design The cohort …

Cervical microRNA expression and spontaneous preterm birth

HH Burris, KD Gerson, A Woodward… - American journal of …, 2023 - Elsevier
ABSTRACT BACKGROUND Preterm birth remains a major public health issue affecting 10%
of all pregnancies and increases risks of neonatal morbidity and mortality. Approximately …

MicroRNA‐transcriptome networks in whole blood and monocytes of women undergoing preterm labour

AG Paquette, O Shynlova, X Wu… - Journal of cellular …, 2019 - Wiley Online Library
Preterm birth is attributed to neonatal morbidity as well as cognitive and physiological
challenges. We have previously identified significant differences in mRNA expression in …

Expression profile of C19MC microRNAs in placental tissue of patients with preterm prelabor rupture of membranes and spontaneous preterm birth

I Hromadnikova, K Kotlabova… - Molecular …, 2017 - spandidos-publications.com
The aim of the study was to demonstrate that preterm birth (PTB) is associated with altered
C19MC microRNA expression profile in placental tissues. Gene expression of 15 placental …

First-trimester maternal cell microRNA is a superior pregnancy marker to immunological testing for predicting adverse pregnancy outcome

EE Winger, JL Reed, X Ji - Journal of reproductive immunology, 2015 - Elsevier
Patients at risk of immune-mediated pregnancy complications have historically relied on the
use of peripheral blood immunological assays for diagnosis and pregnancy monitoring …

First Trimester Prediction of Preterm Delivery in the Absence of Other Pregnancy-Related Complications Using Cardiovascular-Disease Associated MicroRNA …

I Hromadnikova, K Kotlabova, L Krofta - International Journal of Molecular …, 2022 - mdpi.com
The aim of the study was to determine if aberrant expression profile of cardiovascular
disease associated microRNAs would be able to predict within 10 to 13 weeks of gestation …

A history of preterm delivery is associated with aberrant postpartal MicroRNA expression profiles in mothers with an absence of other pregnancy-related complications

I Hromadnikova, K Kotlabova, L Krofta - International Journal of Molecular …, 2021 - mdpi.com
This prospective cross-sectional case-control study investigated the postpartal gene
expression of microRNAs associated with diabetes/cardiovascular/cerebrovascular …