Most neurological disorders seemingly have heterogenous pathogenesis, with overlapping
contribution of neuronal, immune and vascular mechanisms of brain injury. The perivascular …

Although the brain lacks conventional lymphatic vessels found in peripheral tissue, evidence
suggests that the space surrounding the vasculature serves a similar role in the clearance of …

The classic concept of the absence of lymphatic vessels in the central nervous system
(CNS), suggesting the immune privilege of the brain in spite of its high metabolic rate, was …

In at least some individuals who suffer a traumatic brain injury (TBI), there exists a risk of
future neurodegenerative illness. This review focuses on the association between the brain …

Perivascular spaces include a variety of passageways around arterioles, capillaries and
venules in the brain, along which a range of substances can move. Although perivascular …

It is uncontested that perivascular spaces play critical roles in maintaining homeostasis and
priming neuroinflammation. However, despite more than a century of intense research on …

In this article, we provide an overview of current neuroimaging methods for studying
perivascular spaces (PVS) in humans using brain MRI. In recent years, an increasing …

The importance of the perivascular space (PVS) as one of the imaging markers of cerebral
small vessel disease (CSVD) has been widely appreciated by the neuroradiologists. The …

Alzheimer's disease (AD) is a highly damaging disease that affects one's cognition and
memory and presents an increasing societal and economic burden globally. Considerable …

Perivascular spaces (PVS) of the brain, often called Virchow-Robin spaces, comprise fluid,
cells and connective tissue, and are externally limited by astrocytic endfeet. PVS are …