Objective This study leverages public database resources to investigate the cellular and
molecular mechanisms in IgA nephropathy, a major contributor to chronic kidney disease …

The molecular mechanisms underlying renal damage of IgA nephropathy (IgAN) remain
incompletely defined. Here, single-cell RNA sequencing (scRNA-seq) was applied to kidney …

IgA nephropathy (IgAN) is the leading cause of kidney failure due to an incomplete
understanding of its pathogenesis. We perform single-cell RNA sequencing (RNA-seq) on …

Abstract Background and Aims The exact molecular mechanisms underlying IgA
nephropathy (IgAN) remains incompletely defined. Therefore, it is necessary to further …

Abstract Background and Aims Single-nucleus RNA-seq (SnRNA-seq) is a valuable method
for identifying cell-specific transcriptomic alterations in kidney cells. Our objective was to …

A comprehensive profile of genes expressed at the mRNA level (transcriptome) in human
renal tissue is important for elucidating the pathogenesis and treatment of IgA nephropathy …

Abstract Background IgA nephropathy (IgAN) is the most common primary
glomerulonephritis globally. Increasing evidence suggests the importance of host immunity …

Advancements in glomerular transcriptomics offer a promising avenue toward precision
medicine in IgA nephropathy. Traditional prognostic biomarkers, including proteinuria, blood …

Background: IgA nephropathy (IgAN) is one of the most common primary glomerulonephritis
globally. Increasing evidence suggests the importance of host immunity in the development …

Abstract BACKGROUND AND AIMS As the most common glomerulonephritis globally,
mainly affecting younger adults and one of the most common causes of kidney failure, IgA …