Nanopore DNA sequencing with MspA

IM Derrington, TZ Butler, MD Collins… - Proceedings of the …, 2010 - National Acad Sciences
Nanopore sequencing has the potential to become a direct, fast, and inexpensive DNA
sequencing technology. The simplest form of nanopore DNA sequencing utilizes the …

[HTML][HTML] Nucleotide discrimination with DNA immobilized in the MspA nanopore

EA Manrao, IM Derrington, M Pavlenok, M Niederweis… - PloS one, 2011 - journals.plos.org
Nanopore sequencing has the potential to become a fast and low-cost DNA sequencing
platform. An ionic current passing through a small pore would directly map the sequence of …

Reading DNA at single-nucleotide resolution with a mutant MspA nanopore and phi29 DNA polymerase

EA Manrao, IM Derrington, AH Laszlo… - Nature …, 2012 - nature.com
Nanopore technologies are being developed for fast and direct sequencing of single DNA
molecules through detection of ionic current modulations as DNA passes through a pore's …

Decoding long nanopore sequencing reads of natural DNA

AH Laszlo, IM Derrington, BC Ross, H Brinkerhoff… - Nature …, 2014 - nature.com
Nanopore sequencing of DNA is a single-molecule technique that may achieve long reads,
low cost and high speed with minimal sample preparation and instrumentation. Here, we …

Increasing the accuracy of nanopore DNA sequencing using a time-varying cross membrane voltage

MT Noakes, H Brinkerhoff, AH Laszlo… - Nature …, 2019 - nature.com
Nanopore DNA sequencing is limited by low base-calling accuracy. Improved base-calling
accuracy has so far relied on specialized base-calling algorithms, different nanopores and …

Single-molecule DNA detection with an engineered MspA protein nanopore

TZ Butler, M Pavlenok, IM Derrington… - Proceedings of the …, 2008 - National Acad Sciences
Nanopores hold great promise as single-molecule analytical devices and biophysical model
systems because the ionic current blockades they produce contain information about the …

Three decades of nanopore sequencing

D Deamer, M Akeson, D Branton - Nature biotechnology, 2016 - nature.com
A long-held goal in sequencing has been to use a voltage-biased nanoscale pore in a
membrane to measure the passage of a linear, single-stranded (ss) DNA or RNA molecule …

Slowing and controlling the translocation of DNA in a solid-state nanopore

B Luan, G Stolovitzky, G Martyna - Nanoscale, 2012 - pubs.rsc.org
DNA sequencing methods based on nanopores could potentially represent a low-cost and
high-throughput pathway to practical genomics, by replacing current sequencing methods …

DNA sequencing with nanopores

GF Schneider, C Dekker - Nature biotechnology, 2012 - nature.com
DNA sequencing with nanopores | Nature Biotechnology Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain …

Nanopore sequencing: electrical measurements of the code of life

W Timp, UM Mirsaidov, D Wang… - IEEE transactions on …, 2010 - ieeexplore.ieee.org
Sequencing a single molecule of deoxyribonucleic acid (DNA) using a nanopore is a
revolutionary concept because it combines the potential for long read lengths (> 5 kbp) with …