Hamster and ferret experimental infection with intranasal low dose of a single strain of SARS-CoV-2

E Monchatre-Leroy, S Lesellier… - Journal of General …, 2021 - microbiologyresearch.org
Understanding the pathogenesis of the SARS-CoV-2 infection is key to developing
preventive and therapeutic strategies against COVID-19, in the case of severe illness but …

Oral SARS-CoV-2 inoculation establishes subclinical respiratory infection with virus shedding in golden Syrian hamsters

ACY Lee, AJ Zhang, JFW Chan, C Li, Z Fan, F Liu… - Cell Reports …, 2020 - cell.com
Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) is transmitted largely by
respiratory droplets or airborne aerosols. Despite being frequently found in the immediate …

Characterisation and natural progression of SARS-CoV-2 infection in ferrets

GG Au, GA Marsh, AJ McAuley, S Lowther, L Trinidad… - Scientific reports, 2022 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the
infectious disease COVID-19, which has rapidly become an international pandemic with …

Dose-dependent response to infection with SARS-CoV-2 in the ferret model and evidence of protective immunity

KA Ryan, KR Bewley, SA Fotheringham… - Nature …, 2021 - nature.com
There is a vital need for authentic COVID-19 animal models to enable the pre-clinical
evaluation of candidate vaccines and therapeutics. Here we report a dose titration study of …

Host response of Syrian Hamster to SARS-CoV-2 infection including differences with humans and between sexes

M Castellan, G Zamperin, G Franzoni, G Foiani… - Viruses, 2023 - mdpi.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
highlighted the importance of having proper tools and models to study the pathophysiology …

SARS-CoV-2 Omicron variant causes mild pathology in the upper and lower respiratory tract of hamsters

F Armando, G Beythien, FK Kaiser, L Allnoch… - Nature …, 2022 - nature.com
Since its discovery in 2019, multiple variants of severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) have been identified. This study investigates virus spread and …

Defining the Syrian hamster as a highly susceptible preclinical model for SARS-CoV-2 infection

K Rosenke, K Meade-White, M Letko… - Emerging microbes & …, 2020 - Taylor & Francis
Following emergence in late 2019, SARS-CoV-2 rapidly became pandemic and is presently
responsible for millions of infections and hundreds of thousands of deaths worldwide. There …

Protection against reinfection with D614-or G614-SARS-CoV-2 isolates in golden Syrian hamster

M Brustolin, J Rodon… - Emerging microbes & …, 2021 - Taylor & Francis
Reinfections with SARS-CoV-2 have already been documented in humans, although its real
incidence is currently unknown. Besides having a great impact on public health, this …

SARS-CoV-2 causes a systemically multiple organs damages and dissemination in hamsters

Z Song, L Bao, P Yu, F Qi, S Gong, J Wang… - Frontiers in …, 2021 - frontiersin.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has spread across the
world and impacted global healthcare systems. For clinical patients, COVID-19 not only …

Infection with novel coronavirus (SARS-CoV-2) causes pneumonia in Rhesus macaques

C Shan, YF Yao, XL Yang, YW Zhou, G Gao, Y Peng… - Cell research, 2020 - nature.com
The 2019 novel coronavirus (SARS-CoV-2) outbreak is a major challenge for public health.
SARS-CoV-2 infection in human has a broad clinical spectrum ranging from mild to severe …