Abstract Severe coronavirus disease (COVID-19) is characterized by pulmonary hyper-
inflammation and potentially life-threatening “cytokine storms”. Controlling the local and …

Unexpected viral infections outbreaks, significantly affect human health, leading to
increased mortality and life disruption. Among them is the severe acute respiratory …

Active resolution of acute inflammation is a previously unrecognized interface between
innate and adaptive immunity. Once thought to be a passive process, the resolution of …

The resolution of inflammation has emerged as a critical endogenous process that protects
host tissues from prolonged or excessive inflammation that can become chronic. Failure of …

Rationale: Resolution mechanisms are central in both the maintenance of homeostasis and
the return to catabasis following tissue injury and infections. Among the proresolving …

Severe coronavirus disease 2019 (COVID-19) symptoms, including systemic inflammatory
response and multisystem organ failure, are now affecting thousands of infected patients …

The COVID-19 pandemic has raised international awareness of the importance of rigorous
scientific evidence and the havoc caused by uncontrolled excessive inflammation. Here we …

Mounting of the acute inflammatory response is crucial for host defense and pivotal to the
development of chronic inflammation, fibrosis, or abscess formation versus the protective …

Acute inflammation is an indispensable host response to foreign challenges or tissue injury.
In healthy conditions, inflammatory processes are self-limiting and self-resolving, suggesting …

The resolution of the acute inflammatory response is governed by phagocytes actively
clearing apoptotic cells and pathogens. Biosynthesis of the specialized pro-resolving …