Remdesivir use in patients with coronavirus COVID-19 disease: a systematic review and meta-analysis of the Chinese Lancet trial with the NIH trial

PE Alexander, J Piticaru, K Lewis, K Aryal, P Thomas… - MedRXiv, 2020 - medrxiv.org
Abstract Background Coronavirus disease 2019 (COVID-19), caused by the novel
coronavirus SARS-CoV-2, has led to significant global mortality and morbidity. Until now, no …

Remdesivir for treatment of COVID-19; an updated systematic review and meta-analysis

A Rezagholizadeh, S Khiali, P Sarbakhsh… - European journal of …, 2021 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic has become a global health
crisis. Considering the recent food and drug administration (FDA) approval of remdesivir as …

Update on efficacy of the approved remdesivir regimen for treatment of COVID-19: a systematic review with meta-analysis and trial sequential analysis of randomised …

GN Okoli, VK Reddy, OLT Lam, N Askin… - … Medical Research and …, 2024 - Taylor & Francis
Background Efficacy of remdesivir for COVID-19 remains unclear. We updated our
published systematic review to better inform on the use of remdesivir for COVID-19. Methods …

Randomized controlled trials of remdesivir in hospitalized COVID-19 patients: a systematic review and meta-analysis

A Sarfraz, Z Sarfraz, M Sanchez-Gonzalez, J Michel… - Medrxiv, 2020 - medrxiv.org
Background The first cases of the coronavirus disease 2019 (COVID-19) were reported in
Wuhan, China. No antiviral treatment options are currently available with proven clinical …

Remdesivir for the treatment of COVID-19: A systematic review and meta-analysis of randomized controlled trials

A Al-Abdouh, A Bizanti, M Barbarawi, A Jabri… - Contemporary clinical …, 2021 - Elsevier
Background The nucleotide analogue prodrug remdesivir was among the first antiviral
therapies to be tested in randomized controlled trials (RCTs) for COVID-19. We performed a …

Remdesivir for coronavirus disease 2019 (COVID-19): a systematic review with meta-analysis and trial sequential analysis of randomized controlled trials

GN Okoli, R Rabbani, L Copstein, A Al-Juboori… - Infectious …, 2021 - Taylor & Francis
Background In view of many unanswered clinical questions regarding treatment of COVID-
19 with remdesivir, we systematically identified, critically appraised and summarized the …

Efficacy and safety of remdesivir in hospitalized Covid‐19 patients: systematic review and meta‐analysis including network meta‐analysis

HK Elsawah, MA Elsokary, MS Abdallah… - Reviews in medical …, 2021 - Wiley Online Library
Remdesivir is an antiviral agent that has shown broad‐spectrum activity, including against
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Clinical trials investigating …

Remdesivir for the treatment of COVID-19: a living systematic review

F Verdugo-Paiva, P Acuña, I Solá, G Rada… - medRxiv, 2020 - medrxiv.org
Objective This living systematic review aims to provide a timely, rigorous and continuously
updated summary of the evidence available on the role of remdesivir in the treatment of …

Efficacy and safety of remdesivir for Covid-19 treatment: an analysis of randomized, double-blind, placebo-controlled trials

Y Zhu, Z Teng, L Yang, S Xu, J Liu, Y Teng, Q Hao… - medRxiv, 2020 - medrxiv.org
BACKGROUND Remdesivir, an inhibitor of viral RNA-dependent RNA polymerases, has
been identified as a candidate for COVID-19 treatment. However, the therapeutic effect of …

Efficacy and harms of remdesivir for the treatment of COVID-19: A systematic review and meta-analysis

A Piscoya, LF Ng-Sueng, A Parra del Riego… - PloS one, 2020 - journals.plos.org
Background Efficacy and safety of treatments for hospitalized COVID-19 are uncertain. We
systematically reviewed efficacy and safety of remdesivir for the treatment of COVID-19 …