Objectives To investigate the genetic basis of catQ-mediated chloramphenicol resistance in
Streptococcus agalactiae. Methods Two clinical strains of catQ-positive chloramphenicol …

Efflux-mediated macrolide resistance due to mef (E) and mel, carried by the mega element,
is common in Streptococcus pneumoniae, for which it was originally characterized, but it is …

While most integrative and conjugative elements (ICEs) en-code Tyr/Ser recombinases, two
ICE families have recently been described (1) that rely on DDE transposases (2) for …

Objectives The objective of this study was to investigate macrolide-resistant Streptococcus
agalactiae isolates harbouring erm (TR), an erm (A) gene subclass, with emphasis on their …

ICE Sag37, a novel integrative and conjugative element carrying multidrug resistance and
potential virulence factors, was characterized in a clinical isolate of Streptococcus …

In streptococci mef (I) and catQ, two relatively uncommon macrolide and chloramphenicol
resistance genes, respectively, are typically linked in a genetic module designated IQ …

Mobile genetic elements (MGEs), such as integrative and conjugative elements (ICEs),
plasmids and translocatable units (TUs), are important drivers for the spread of antibiotic …

Integrative and conjugative elements (ICEs) are important vectors of lateral gene transfer
and contribute to the evolution of bacterial pathogens. However, studies on the transfer …

Streptococcus agalactiae (group B streptococcus [GBS]) is the leading cause of neonatal
and maternal sepsis. Penicillin is recommended for intrapartum prophylaxis, but …

ABSTRACT ICE Sp1116, responsible for erm (B)-mediated, inducible erythromycin
resistance in Streptococcus pyogenes, was comprehensively characterized, and its …