Low testosterone and sex hormone-binding globulin levels and high estradiol levels are independent predictors of type 2 diabetes in men

T Vikan, H Schirmer, I Njølstad… - European journal of …, 2010 - academic.oup.com
Objective To study the impact of endogenous sex hormone levels in community-dwelling
men on later risk for type 2 diabetes. Design Population-based prospective cohort study …

Serum testosterone, sex hormone‐binding globulin and sex‐specific risk of incident type 2 diabetes in a retrospective primary care cohort

MW O'Reilly, M Glisic, B Kumarendran… - Clinical …, 2019 - Wiley Online Library
Objective Previous studies suggest that androgens have a sexually dimorphic impact on
metabolic dysfunction. However, the sex‐specific link between circulating androgens and …

Testosterone levels and type 2 diabetes—no correlation with age, differential predictive value in men and women

M Karakas, S Schäfer, S Appelbaum, F Ojeda… - Biomolecules, 2018 - mdpi.com
Most studies reporting on the association of circulating testosterone levels with type 2
diabetes in men are of cross-sectional design. Reports on the relevance of altered …

Sex differences of endogenous sex hormones and risk of type 2 diabetes: a systematic review and meta-analysis

EL Ding, Y Song, VS Malik, S Liu - Jama, 2006 - jamanetwork.com
ContextInconsistent data suggest that endogenous sex hormones may have a role in sex-
dependent etiologies of type 2 diabetes, such that hyperandrogenism may increase risk in …

Low testosterone: a risk marker rather than a risk factor for type 2 diabetes

SA Holmboe, TK Jensen, A Linneberg… - The Journal of …, 2016 - academic.oup.com
Context: Low serum T levels have been associated with type 2 diabetes (T2D) and
cardiovascular disease. However, it is unresolved whether low T is a risk factor or rather a …

Testosterone and sex hormone–binding globulin predict the metabolic syndrome and diabetes in middle-aged men

DE Laaksonen, L Niskanen, K Punnonen… - Diabetes …, 2004 - Am Diabetes Assoc
OBJECTIVE—In men, hypoandrogenism is associated with features of the metabolic
syndrome, but the role of sex hormones in the pathogenesis of the metabolic syndrome and …

Endogenous sex hormones and the development of type 2 diabetes in older men and women: the Rancho Bernardo study

JY Oh, E Barrett-Connor, NM Wedick… - Diabetes …, 2002 - Am Diabetes Assoc
OBJECTIVE—To determine the prospective association between endogenous sex
hormones and the development of type 2 diabetes in older men and women. RESEARCH …

The role of sex hormone-binding globulin (SHBG), testosterone, and other sex steroids, on the development of type 2 diabetes in a cohort of community-dwelling …

P Gyawali, SA Martin, LK Heilbronn, AD Vincent… - Acta …, 2018 - Springer
Aims Contrasting findings exist regarding the association between circulating sex hormone-
binding globulin (SHBG) and testosterone levels and type 2 diabetes (T2D) in men. We …

The association of endogenous sex hormones, adiposity, and insulin resistance with incident diabetes in postmenopausal women

RR Kalyani, M Franco, AS Dobs… - The Journal of …, 2009 - academic.oup.com
Context: In postmenopausal women, endogenous bioavailable testosterone (T) and
estradiol (E2) have been positively associated, and SHBG has been negatively associated …

Testosterone, SHBG and risk of type 2 diabetes in the second evaluation of the Pizarra cohort study

F Soriguer, E Rubio‐Martín… - European journal of …, 2012 - Wiley Online Library
Eur J Clin Invest 2012; 42 (1): 79–85 Abstract Aim To evaluate the association between
serum levels of testosterone, sex hormone‐binding globulin (SHBG) and calculated …