Association of pharmacological interventions with symptom burden reduction in patients with mild traumatic brain injury: a systematic review

C Feinberg, C Carr, R Zemek, KO Yeates… - JAMA …, 2021 - jamanetwork.com
Importance Mild traumatic brain injury (TBI) is experienced by 55.9 million people globally
each year. The symptoms of mild TBI are diverse and sometimes long-lasting, requiring …

Overview of pharmacological interventions after traumatic brain injuries: impact on selected outcomes

S Kim, M Mortera, X Hu, S Krishnan, L Hoffecker… - Brain injury, 2019 - Taylor & Francis
The purpose of this study was to conduct an overview of systematic reviews (SRs) to
appraise the published evidence related to pharmacological interventions after traumatic …

[HTML][HTML] Interventions provided in the acute phase for mild traumatic brain injury: a systematic review

J Gravel, A D'Angelo, B Carrière, L Crevier… - Systematic reviews, 2013 - Springer
Background Most patients who sustain mild traumatic brain injury (mTBI) have persistent
symptoms at 1 week and 1 month after injury. This systematic review investigated the …

Traumatic brain injury clinical practice guidelines and best practices from the VA state of the art conference

J Scholten, JJ Vasterling, JB Grimes - Brain injury, 2017 - Taylor & Francis
Management of symptoms following traumatic brain injury (TBI) can be complex and
remains a high priority for Department of Defense (DoD) and Department of Veteran Affairs …

Pharmacological interventions in traumatic brain injury: Can we rely on systematic reviews for evidence?

R Gultekin, S Huang, O Clavisi, L Pattuwage, TC König… - Injury, 2016 - Elsevier
Introduction Providing current, reliable and evidence based information for clinicians and
researchers in a synthesised and summarised way can be challenging particularly in the …

A systematic review of reported outcomes in randomized controlled trials targeting early interventions in moderate-to-severe traumatic brain injury

Y Derouin, T Delhomme, Y Launey, M Bouras… - Journal of …, 2024 - liebertpub.com
Traumatic brain injury (TBI) is a leading cause of death and disability worldwide.
Randomized controlled trials (RCTs) are the cornerstone to evaluate the efficacy of an …

A state-of-the-science overview of randomized controlled trials evaluating acute management of moderate-to-severe traumatic brain injury

P Bragge, A Synnot, AI Maas, DK Menon… - Journal of …, 2016 - liebertpub.com
Moderate-to-severe traumatic brain injury (TBI) remains a major global challenge, with rising
incidence, unchanging mortality and lifelong impairments. State-of-the-science reviews are …

Pharmacotherapy for mild traumatic brain injury: an overview of the current treatment options

C Gao, M Nie, J Huang, Y Tian, D Wang… - Expert opinion on …, 2022 - Taylor & Francis
Introduction Accounting for 90% of all traumatic brain injuries (TBIs), mild traumatic brain
injury (mTBI) is currently the most frequently seen type of TBI. Although most patients can …

Practice patterns in pharmacological and non-pharmacological therapies for children with mild traumatic brain injury: a survey of 15 Canadian and United States …

R Mannix, R Zemek, KO Yeates, K Arbogast… - Journal of …, 2019 - liebertpub.com
Given the lack of evidence regarding effective pharmacological and non-pharmacological
interventions for pediatric mild traumatic brain injury (mTBI) and the resultant lack of …

Risk factors for high symptom burden three months after traumatic brain injury and implications for clinical trial design: a transforming research and clinical knowledge …

N Temkin, J Machamer, S Dikmen, LD Nelson… - Journal of …, 2022 - liebertpub.com
More than 75% of patients presenting to level I trauma centers in the United States with
suspicion of TBI sufficient to require a clinical computed tomography scan report injury …