AP-1 transcription factors play a critical role in signal transduction pathways in many cells.
We have investigated the role of AP-1 in controlling proliferative signals in breast cells, and …

The AP-1 transcription factor is a central component of signal transduction pathways in many
cells, although the exact role of AP-1 in controlling cell growth and malignant transformation …

We have previously demonstrated that basal AP-1 transcriptional activity is high in normal
human mammary epithelial cells, intermediate in immortal breast cells, and relatively low in …

The AP-2 transcription factors are required for normal growth and morphogenesis during
mammalian development. Previous in vitro studies have also indicated that the AP-2 family …

We have studied the expression and activity of the jun and fos families of transcription
factors in a panel of human breast cancer cells. Numerous breast‐cancer cell lines showed …

The AP2 transcription factors exhibit a high degree of homology in the DNA binding and
dimerization domains. In this study, we methodically compared the binding specificity of …

The AP-1 transcription factor is activated by multiple growth factors that are critical regulators
of breast cell proliferation. We previously demonstrated that AP-1 blockade inhibits breast …

Abstract The activating protein-1 (AP-1) transcription factor transduces growth signals
through signal transduction pathways to the nucleus, leading to the expression of genes …

We have studied the role of the AP1 transcription factor in the progression of human breast
carcinomas. This progression is characterized by a loss of dependence for proliferation on …

Purpose: We proposed to investigate the expression and prognostic significance of activator
protein 2 (AP-2) in breast cancer. Experimental Design: AP-2 was immunohistochemically …