Simple Summary Hepsin is a serine protease whose deregulation leads to tumor invasion
and metastasis in many tumor types. In colorectal cancer, the role of hepsin is unknown, so …

In light of the poor prognosis for ovarian cancer patients, the research continues for
innovative and efficacious treatment modalities. Along with surgical and chemotherapeutic …

Background/Aims: Hepsin is a type II transmembrane protein predominantly expressed in
the liver and has been implicated in participation in blood coagulation pathway and …

[Frontiers in Bioscience 12, 5052-5059, September 1, 2007] 5052 Hepsin and prostate cancer
Qingyu Wu1, Gordon Parry2 1Department Page 1 [Frontiers in Bioscience 12, 5052-5059 …

Hepsin is a membrane-anchored serine protease whose role in hepatocyte growth factor
(HGF) signaling and epithelial integrity makes it a target of therapeutic interest in …

Hepsin, a type‐II membrane‐associated serine protease, has been implicated in cell growth
and developement as well as possible initiation of blood coagulation. Here, we report on the …

Hepsin, a cell surface protease, is widely reported to be overexpressed in more than 90% of
human prostate tumors. Hepsin expression correlates with tumor progression, making it a …

Hepsin is a type II transmembrane serine protease highly expressed on the surface of
hepatocytes. The physiological function of hepsin is not known, although in vitro studies …

Hepsin, a putative membrane-bound serine protease, was originally identified as a human
liver cDNA clone (Leytus, SP, Loeb, KR, Hagen, FS, Kurachi, K., and Davie, EW (1988) …

Transforming growth factor‐beta (TGFβ) is a multifunctional cytokine with a well‐established
role in mammary gland development and both oncogenic and tumor‐suppressive functions …