[HTML][HTML] Vascular risk factors and astrocytic marker for the glymphatic system activity

YC Wei, CCH Hsu, WY Huang, C Lin, CK Chen… - La radiologia …, 2023 - Springer
Objectives Glymphatic system maintains brain fluid circulation via active transportation of
astrocytic aquaporin-4 in perivascular space. The diffusion tensor imaging analysis along …

[HTML][HTML] The glymphatic system: a new perspective on brain diseases

Z Ding, X Fan, Y Zhang, M Yao, G Wang… - Frontiers in Aging …, 2023 - frontiersin.org
The glymphatic system is a brain-wide perivascular pathway driven by aquaporin-4 on the
endfeet of astrocytes, which can deliver nutrients and active substances to the brain …

[HTML][HTML] The influence of demographics and vascular risk factors on glymphatic function measured by diffusion along perivascular space

Y Zhang, R Zhang, Y Ye, S Wang, Y Jiaerken… - Frontiers in Aging …, 2021 - frontiersin.org
Assessing glymphatic function using in-vivo imaging method is of great value for
understanding its contribution to major brain diseases. In the present study, we aim to …

Glymphatic function plays a protective role in ageing-related cognitive decline

J Wang, Y Zhou, K Zhang, W Ran, X Zhu… - Age and …, 2023 - academic.oup.com
Objective The glymphatic pathway, characterised as a cerebral drainage system, influences
cognitive function in neurodegenerative diseases; however, evidence is limited in a normal …

The glymphatic system's role in traumatic brain injury-related neurodegeneration

ME Peters, CG Lyketsos - Molecular psychiatry, 2023 - nature.com
In at least some individuals who suffer a traumatic brain injury (TBI), there exists a risk of
future neurodegenerative illness. This review focuses on the association between the brain …

[HTML][HTML] The glymphatic system: a novel therapeutic target for stroke treatment

T Lv, B Zhao, Q Hu, X Zhang - Frontiers in Aging Neuroscience, 2021 - frontiersin.org
The glymphatic system (GS) is a novel defined brain-wide perivascular transit network
between cerebrospinal fluid (CSF) and interstitial solutes that facilitates the clearance of …

Current concepts in intracranial interstitial fluid transport and the glymphatic system: part II—imaging techniques and clinical applications

JM Klostranec, D Vucevic, KD Bhatia, HGJ Kortman… - Radiology, 2021 - pubs.rsna.org
The glymphatic system is a recently discovered network unique to the central nervous
system that allows for dynamic exchange of interstitial fluid (ISF) and cerebrospinal fluid …

[HTML][HTML] Glymphatic system in the central nervous system, a novel therapeutic direction against brain edema after stroke

X Zhou, Y Li, C Lenahan, Y Ou, M Wang… - Frontiers in Aging …, 2021 - frontiersin.org
Stroke is the destruction of brain function and structure, and is caused by either
cerebrovascular obstruction or rupture. It is a disease associated with high mortality and …

Glymphatic system evaluation using diffusion tensor imaging in patients with traumatic brain injury

JH Park, YJ Bae, JS Kim, WS Jung, JW Choi, TH Roh… - Neuroradiology, 2023 - Springer
Purpose Glymphatic system dysfunction has been reported in animal models of traumatic
brain injury (TBI). This study aimed to evaluate the activity of the human glymphatic system …

[HTML][HTML] Glymphatic imaging: a critical look at the DTI-ALPS index

G Ringstad - Neuroradiology, 2024 - Springer
Derived from rodent studies, the glymphatic system was described in 2012 as a pathway
facilitating perivascular clearance of solutes from the brain interstitial fluid (ISF)[1]. The term …