Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic options

Y Nazerian, M Ghasemi, Y Yassaghi, A Nazerian… - International …, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) outbreak has become a global public health
emergency and has led to devastating results. Mounting evidence proposes that the disease …

Features of cytokine storm identified by distinguishing clinical manifestations in COVID-19

WX Shen, RC Luo, JQ Wang, ZS Chen - Frontiers in public health, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is caused by a new coronavirus, namely severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is currently spreading all over …

An inter-correlated cytokine network identified at the center of cytokine storm predicted COVID-19 prognosis

Y Liu, D Chen, J Hou, H Li, D Cao, M Guo, Y Ling… - Cytokine, 2021 - Elsevier
The hyper-inflammatory response is thought to be a major cause of acute respiratory
distress syndrome (ARDS) in patients with COVID-19. Although multiple cytokines are …

[HTML][HTML] The COVID-19 cytokine storm; what we know so far

D Ragab, H Salah Eldin, M Taeimah… - Frontiers in …, 2020 - frontiersin.org
COVID-19 is a rapidly spreading global threat that has been declared as a pandemic by the
WHO. COVID-19 is transmitted via droplets or direct contact and infects the respiratory tract …

Scoring cytokine storm by the levels of MCP-3 and IL-8 accurately distinguished COVID-19 patients with high mortality

L Chen, G Wang, J Tan, Y Cao, X Long, H Luo… - … and Targeted Therapy, 2020 - nature.com
Coronavirus disease 2019 (COVID-19) is a global-spread infectious disease caused by a
novel coronavirus, SARS-CoV-2. 1 COVID-19 causes heterogeneous disease phenotype, of …

Sepsis-associated severe interleukin-6 storm in critical coronavirus disease 2019

L Huang, X Zhao, Y Qi, H Li, G Ye, Y Liu… - Cellular & molecular …, 2020 - nature.com
Coronavirus disease 2019 (COVID-19) is a respiratory disease caused by a novel
coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). 1, 2 …

Cytokine storm: the primary determinant for the pathophysiological evolution of COVID-19 deterioration

R Chen, Z Lan, J Ye, L Pang, Y Liu, W Wu… - Frontiers in …, 2021 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic caused by the novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing major threat to global …

[PDF][PDF] An update on cytokine storm in covid-19 infection: Pivotal to the survival of the patients

EI Obeagu, S Hamisi, UO Bunu - Int. J. Adv. Res. Biol. Sci, 2023 - researchgate.net
The immune system protects the host organism from exogenous and endogenouspathogens
. A finely tuned and balanced array of cytokines, coagulation factors, andcomplement …

SARS-CoV-2 causes a different cytokine response compared to other cytokine storm-causing respiratory viruses in severely ill patients

M Olbei, I Hautefort, D Modos, A Treveil… - Frontiers in …, 2021 - frontiersin.org
Hyper-induction of pro-inflammatory cytokines, also known as a cytokine storm or cytokine
release syndrome (CRS), is one of the key aspects of the currently ongoing SARS-CoV-2 …

[PDF][PDF] Cytokine storms caused by novel coronavirus 2019 and treatment for cardiac injury.

DM Zhang, SL Chen - European Review for Medical & …, 2020 - europeanreview.org
Since December 2019, an outbreak of a new coronavirus, COVID-19, infection has been
taking place. At present, COVID-19 has spread to most countries worldwide. The latest …