Circulating levels of interleukin-6 and interleukin-10, but not tumor necrosis factor-alpha, as potential biomarkers of severity and mortality for COVID-19: systematic …

W Udomsinprasert, J Jittikoon… - Journal of clinical …, 2021 - Springer
Purpose Cytokine storm, an uncontrolled overproduction of inflammatory cytokines
contributing to an aberrant systemic inflammatory response, is a major pathological feature …

Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines

A Fara, Z Mitrev, RA Rosalia, BM Assas - Open biology, 2020 - royalsocietypublishing.org
Coronavirus disease 2019 (COVID-19) has swept the world, unlike any other pandemic in
the last 50 years. Our understanding of the disease has evolved rapidly since the outbreak; …

[PDF][PDF] Treatment of the Cytokine Storm in COVID-19

B Halacli, A Topeli - J Crit Intensive Care, 2020 - researchgate.net
Cytokine storm has been proposed as the basis of the pathophysiological process of COVID-
19 caused by SARS-CoV-2. Cytokine storm, generally known as excessive or uncontrolled …

Cytokine release syndrome in COVID-19: a major mechanism of morbidity and mortality

Y Que, C Hu, K Wan, P Hu, R Wang, J Luo… - International reviews …, 2022 - Taylor & Francis
Abstract The coronavirus disease 2019 (COVID-19) triggered by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) erupted in Hubei Province of China in December …

Cytokines and COVID-19: friends or foes?

M Rokni, MR Hamblin, N Rezaei - Human vaccines & …, 2020 - Taylor & Francis
The cytokine storm following sepsis has been proven to be an important mechanism for
triggering acute respiratory distress syndrome, which is a fatal uncontrolled systemic …

Cytokine release syndrome in severe COVID-19: interleukin-6 receptor antagonist tocilizumab may be the key to reduce mortality

C Zhang, Z Wu, JW Li, H Zhao, GQ Wang - International journal of …, 2020 - Elsevier
Since December 2019, a viral pneumonia, named coronavirus disease 2019 (COVID-19),
from Wuhan, China, has swept the world. Although the case fatality rate is not high, the …

COVID-19 cytokine storm syndrome: a threshold concept

LYC Chen, TTT Quach - The Lancet Microbe, 2021 - thelancet.com
The COVID-19 pandemic has placed the practice of medicine at a threshold overlooking a
new and different era, 1 and has led to the evolving concept of COVID-19 cytokine storm …

Cytokine and cytokine storm.

YL Wang, F Wang, J Geng - 2020 - cabidigitallibrary.org
Cytokines are a diverse group of small molecule proteins or peptides that are secreted by
cells for the purpose of intercellular delivery signaling and communication, which play an …

Cytokine storm and histopathological findings in 60 cases of COVID-19-related death: from viral load research to immunohistochemical quantification of major players …

P Frisoni, M Neri, S D'Errico, L Alfieri… - … Science, Medicine and …, 2022 - Springer
This study involves the histological analysis of samples taken during autopsies in cases of
COVID-19 related death to evaluate the inflammatory cytokine response and the tissue …

[HTML][HTML] Clinical characteristics of 25 death cases with COVID-19: a retrospective review of medical records in a single medical center, Wuhan, China

X Li, L Wang, S Yan, F Yang, L Xiang, J Zhu… - International Journal of …, 2020 - Elsevier
Objectives This study aims to summarize the clinical characteristics of death cases with
COVID-19 and to identify critically ill patients of COVID-19 early and reduce their mortality …