There are multiple clocks that time us: Cross-sectional and longitudinal associations among 14 alternative indicators of age and aging

J Drewelies, J Homann, V Vetter, S Duezel, S Kühn… - 2023 - researchsquare.com
Aging is a complex process influenced by mechanisms operating at numerous levels of
functioning. Multiple biomarkers of age have been identified, yet we know little about how …

Longitudinal phenotypic aging metrics in the Baltimore Longitudinal Study of Aging

PL Kuo, JA Schrack, ME Levine, MD Shardell… - Nature aging, 2022 - nature.com
To define metrics of phenotypic aging, it is essential to identify biological and environmental
factors that influence the pace of aging. Previous attempts to develop aging metrics were …

Quest for a summary measure of biological age: the health and retirement study

EM Crimmins, B Thyagarajan, JK Kim, D Weir, J Faul - Geroscience, 2021 - Springer
Measures of biological age and its components have been shown to provide important
information about individual health and prospective change in health as there is clear value …

The Sociodemographic and Lifestyle Correlates of Epigenetic Aging in a Nationally Representative US Study of Younger Adults

KM Harris, B Levitt, L Gaydosh, C Martin, JM Meyer… - bioRxiv, 2024 - biorxiv.org
Importance Epigenetic clocks represent molecular evidence of disease risk and aging
processes and have been used to identify how social and lifestyle characteristics are …

How does subjective age get “under the skin”? The association between biomarkers and feeling older or younger than one's age: The Health and Retirement Study

B Thyagarajan, N Shippee, H Parsons… - Innovation in …, 2019 - academic.oup.com
Abstract Background and Objectives Though subjective age is a well-recognized risk factor
for several chronic diseases, the biological basis for these associations remains poorly …

Sex differences in biological aging and the association with clinical measures in older adults

AZZ Phyo, PD Fransquet, J Wrigglesworth, RL Woods… - GeroScience, 2024 - Springer
Females live longer than males, and there are sex disparities in physical health and disease
incidence. However, sex differences in biological aging have not been consistently reported …

[HTML][HTML] A catalogue of omics biological ageing clocks reveals substantial commonality and associations with disease risk

E Macdonald-Dunlop, N Taba, L Klarić… - Aging (Albany …, 2022 - ncbi.nlm.nih.gov
Biological age (BA), a measure of functional capacity and prognostic of health outcomes that
discriminates between individuals of the same chronological age (chronAge), has been …

FEELING YOUNGER, BEING YOUNGER: ASSOCIATIONS BETWEEN BIOLOGICAL AGE AND SUBJECTIVE AGE IN OLDER ADULTS

J Drewelies, I Demuth, S Duezel, G Hueluer… - Innovation in …, 2019 - ncbi.nlm.nih.gov
Subjective age has been shown to be a strong predictor of both subjective and objective
health outcomes. However, little is known about the extent to which individuals' subjective …

Clarifying the biological and statistical assumptions of cross-sectional biological age predictors

MH Sluiskes, JJ Goeman, M Beekman, PE Slagboom… - bioRxiv, 2023 - biorxiv.org
There is variability in the rate of aging among people of the same chronological age. The
concept of biological age is postulated to capture this variability, and hence to better …

System specific aging scores: a state of the art aging clock built using aging scores from different bodily functions

R Sehgal, A Higgins-Chen, M Meer… - Innovation in Aging, 2022 - academic.oup.com
Aging is a highly heterogeneous process at multiple levels. Different individuals, organs,
tissues, and cell types are innately diverse and age in quantitatively different manners …