The freshwater Hydra polyp provides a unique model system to decipher the mechanisms
underlying adult regeneration. Indeed, a single cut initiates two distinct regenerative …

Decapitated Hydra regenerate their heads via morphallaxis, ie, without significant
contributions made by cell proliferation or interstitial stem cells. Indeed, Hydra depleted of …

After bisection, Hydra polyps regenerate their head from the lower half thanks to a head‐
organizer activity that is rapidly established at the tip. Head regeneration is also highly …

Over the past decades, genetic analyses performed in vertebrate and invertebrate
organisms deciphered numerous cellular and molecular mechanisms deployed during …

The Hydra model system is well suited for the eludication of the mechanisms underlying
regeneration in the adult, and an understanding of the core mechanisms is likely to cast light …

Hydra freswater polyps have a remarkable ability to regenerate after bisection or even after
dissociation, and thus offer a unique model system to investigate the cellular and molecular …

Wnt/β-Catenin signaling plays crucial roles in regenerative processes in eumetazoans. It
also acts in regeneration and axial patterning in the simple freshwater polyp Hydra, whose …

Here we discuss the developmental and homeostatic conditions necessary for Hydra
regeneration. Hydra is characterized by populations of adult stem cells paused in the G2 …

Hydra's almost unlimited regenerative potential is based on Wnt signaling, but so far it is
unknown how the injury stimulus is transmitted to discrete patterning fates in head and foot …

Wnt genes and β-Catenin signaling are involved in axial patterning processes in vertebrate
embryogenesis in setting up the Spemann–Mangold organizer in amphibian embryos. An …