The use of estimated glomerular filtration rate for dose adjustment of medications in the elderly
CG Elinder, P Bárány, O Heimbürger - Drugs & aging, 2014 - Springer
Adverse drug effects as a consequence of inappropriate dosage are a common cause of
hospitalization among the elderly. Older individuals are at a particular risk of overdosing …
hospitalization among the elderly. Older individuals are at a particular risk of overdosing …
Kidney function and clinical recommendations of drug dose adjustment in geriatric patients
M Karsch-Völk, E Schmid, S Wagenpfeil, K Linde… - BMC geriatrics, 2013 - Springer
Background In elderly patients chronic kidney disease often limits drug prescription. As
several equations for quick assessment of kidney function by estimating glomerular filtration …
several equations for quick assessment of kidney function by estimating glomerular filtration …
Comparison of estimated glomerular filtration rate with estimated creatinine clearance in the dosing of drugs requiring adjustments in elderly patients with declining …
WJ Spruill, WE Wade, HH Cobb III - The American journal of geriatric …, 2008 - Elsevier
Background: The National Kidney Foundation's practice guidelines for chronic kidney
disease recommend using the Modification of Diet in Renal Disease (MDRD) equation for …
disease recommend using the Modification of Diet in Renal Disease (MDRD) equation for …
Estimating renal function to reduce the risk of adverse drug reactions
The aging process is characterized by relevant changes in pharmacokinetics. Renal function
is known to decline with aging. However, as a result of reduced muscle mass, older …
is known to decline with aging. However, as a result of reduced muscle mass, older …
Clinical relevance of differences in glomerular filtration rate estimations in frail older people by creatinine-vs. cystatin C-based formulae
A Jacobs, C Benraad, J Wetzels, MO Rikkert… - Drugs & aging, 2017 - Springer
Background The risk of incorrect medication dosing is high in frail older people. Therefore,
accurate assessment of the glomerular filtration rate is important. Objective The objective of …
accurate assessment of the glomerular filtration rate is important. Objective The objective of …
Interest and limits of glomerular filtration rate (GFR) estimation with formulae using creatinine or cystatin C in the malnourished elderly population
EE Fabre, A Raynaud-Simon, JL Golmard… - Bio tribune …, 2010 - Springer
Renal function is often altered in elderly patients. A lot of formulae are proposed to estimate
GFR to adjust drug posology. French guidelines recommend the Cockcroft-Gault formula …
GFR to adjust drug posology. French guidelines recommend the Cockcroft-Gault formula …
Kidney function estimates using cystatin C versus creatinine: Impact on medication prescribing in acutely hospitalized elderly patients
E Iversen, AC Bodilsen, HH Klausen… - Basic & clinical …, 2019 - Wiley Online Library
Background Medication errors due to inaccurate measures of kidney function are common
among elderly patients. We investigated differences between estimated glomerular filtration …
among elderly patients. We investigated differences between estimated glomerular filtration …
Estimated glomerular filtration rate leads to higher drug dose recommendations in the elderly compared with creatinine clearance
JQ Hudson, JR Bean, CF Burger… - … Journal of Clinical …, 2015 - Wiley Online Library
Purpose The elderly are at risk for adverse drug events because of inappropriate dosing of
renally eliminated medications. The purpose of this study was to evaluate differences in …
renally eliminated medications. The purpose of this study was to evaluate differences in …
Reconsideration of the current models of estimated kidney function‐based drug dose adjustment in older adults: The role of biological age
R Alikhani, MP Pai - Clinical and Translational Science, 2023 - Wiley Online Library
Human lifespan has increased from a median of 46.5 years in 1950 to 71.7 years in 2022.
As people age, one of the inevitable consequences is a decline in kidney function and …
As people age, one of the inevitable consequences is a decline in kidney function and …
Changes in renal function with aging: implications for treatment
RD Lindeman - Drugs & aging, 1992 - Springer
The most important clinical renal function to monitor with aging is the glomerular filtration
rate (creatinine clearance). Most decisions on drug dosage can be based on this information …
rate (creatinine clearance). Most decisions on drug dosage can be based on this information …