Human lung small airway-on-a-chip protocol
Organs-on-chips are microfluidic cell culture devices created using microchip manufacturing
techniques that contain hollow microchannels lined by living cells, which recreate …
techniques that contain hollow microchannels lined by living cells, which recreate …
Microfabrication of human organs-on-chips
Abstract'Organs-on-chips' are microengineered biomimetic systems containing microfluidic
channels lined by living human cells, which replicate key functional units of living organs to …
channels lined by living human cells, which replicate key functional units of living organs to …
A biomimetic multicellular model of the airways using primary human cells
KL Sellgren, EJ Butala, BP Gilmour, SH Randell… - Lab on a Chip, 2014 - pubs.rsc.org
Microfluidic cell cultures enable investigation of complex physiological tissue properties and
functionalities. For convenience, they are often implemented with immortalized cell lines, but …
functionalities. For convenience, they are often implemented with immortalized cell lines, but …
A 96-well format microvascularized human lung-on-a-chip platform for microphysiological modeling of fibrotic diseases
Development of organoids and microfluidic on-chip models has enabled studies of organ-
level disease pathophysiologies in vitro. However, current lung-on-a-chip platforms are …
level disease pathophysiologies in vitro. However, current lung-on-a-chip platforms are …
Microfluidic lung airway-on-a-chip with arrayable suspended gels for studying epithelial and smooth muscle cell interactions
Chronic lung diseases (CLDs) are regulated by complex interactions between many
different cell types residing in lung airway tissues. Specifically, interactions between airway …
different cell types residing in lung airway tissues. Specifically, interactions between airway …
Human microphysiological models of airway and alveolar epithelia
DA Lagowala, S Kwon, VK Sidhaye… - American Journal of …, 2021 - journals.physiology.org
Human organ-on-a-chip models are powerful tools for preclinical research that can be used
to study the mechanisms of disease and evaluate new targets for therapeutic intervention …
to study the mechanisms of disease and evaluate new targets for therapeutic intervention …
What can an organ-on-a-chip teach us about human lung pathophysiology?
The intertwined relationship between structure and function has been key to understanding
human organ physiology and disease pathogenesis. An organ-on-a-chip (organ chip) is a …
human organ physiology and disease pathogenesis. An organ-on-a-chip (organ chip) is a …
Engineering organ-on-a-chip to accelerate translational research
We guide the use of organ-on-chip technology in tissue engineering applications. Organ-on-
chip technology is a form of microengineered cell culture platform that elaborates the in-vivo …
chip technology is a form of microengineered cell culture platform that elaborates the in-vivo …
Three-dimensional co-cultures of human endothelial cells and embryonic stem cell-derived pericytes inside a microfluidic device
Organs-on-chips are microengineered in vitro tissue structures that can be used as platforms
for physiological and pathological research. They provide tissue-like microenvironments in …
for physiological and pathological research. They provide tissue-like microenvironments in …
Microfluidic organs-on-chips
An organ-on-a-chip is a microfluidic cell culture device created with microchip manufacturing
methods that contains continuously perfused chambers inhabited by living cells arranged to …
methods that contains continuously perfused chambers inhabited by living cells arranged to …