Galcanezumab in patients with episodic migraine: results from the open-label period of the phase 3 PERSIST study

J Zhou, L Zhong, D Chowdhury… - The Journal of …, 2023 - Springer
Background The phase 3 randomized PERSIST study demonstrated the efficacy and
tolerability of galcanezumab, a humanized anti-calcitonin gene-related peptide (CGRP) …

Long-term effectiveness and tolerability of galcanezumab in patients with migraine excluded from clinical trials: real world evidence of 1055 patients with 1 year follow …

V Obach, F Velasco, R Alvarez Escudero… - The Journal of …, 2023 - Springer
Background Galcanezumab has shown efficacy and effectiveness in the treatment of
episodic and chronic migraine (CM), however, the population represented in randomized …

100% response rate to galcanezumab in patients with episodic migraine: A post hoc analysis of the results from phase 3, randomized, double‐blind, placebo …

N Rosen, E Pearlman, D Ruff, K Day… - … : The Journal of Head …, 2018 - Wiley Online Library
Objective To characterize adult patients with episodic migraine who achieved 100%
response to galcanezumab treatment. Background Galcanezumab is a humanized …

Galcanezumab in episodic migraine: the phase 3, randomized, double-blind, placebo-controlled PERSIST study

B Hu, G Li, X Li, S Wu, T Yu, X Li, H Zhao, Z Jia… - The Journal of …, 2022 - Springer
Background Galcanezumab, a humanized monoclonal antibody that binds calcitonin gene-
related peptide, has demonstrated efficacy and good tolerability in patients with episodic …

Long-term treatment with galcanezumab in patients with chronic migraine: results from the open-label extension of the REGAIN study

P Pozo-Rosich, HC Detke, S Wang… - Current Medical …, 2022 - Taylor & Francis
Background Galcanezumab, a monoclonal antibody to calcitonin gene-related peptide, was
found to be safe and efficacious for the preventive treatment of chronic migraine based on …

Safety of galcanezumab in patients with episodic migraine: a randomized placebo-controlled dose-ranging phase 2b study

TMM Oakes, V Skljarevski, Q Zhang… - …, 2018 - journals.sagepub.com
Background Safety findings from a Phase 2b study of galcanezumab, a humanized
monoclonal antibody against calcitonin gene-related peptide, for prevention of migraine …

A phase 3, long-term, open-label safety study of Galcanezumab in patients with migraine

A Camporeale, D Kudrow, R Sides, S Wang… - BMC neurology, 2018 - Springer
Background Galcanezumab, a humanized monoclonal antibody that selectively binds to the
calcitonin gene-related peptide, has demonstrated in previous Phase 2 and Phase 3 clinical …

Rapid onset of effect of galcanezumab for the prevention of episodic migraine: analysis of the EVOLVE studies

HC Detke, BA Millen, Q Zhang… - … : The Journal of …, 2020 - Wiley Online Library
Objective To evaluate onset of effect of galcanezumab in patients with episodic migraine.
Background Galcanezumab is a monoclonal antibody that binds to calcitonin gene‐related …

Galcanezumab in episodic migraine: subgroup analyses of efficacy by high versus low frequency of migraine headaches in phase 3 studies (EVOLVE-1 & EVOLVE-2)

SD Silberstein, VL Stauffer, KA Day, S Lipsius… - The Journal of …, 2019 - Springer
Background Patients with high-frequency episodic migraine (HFEM) have a greater disease
burden than those with low-frequency episodic migraine (LFEM). Acute treatment overuse …

Galcanezumab provides consistent efficacy throughout the dosing interval among patients with episodic and chronic migraine: a post hoc analysis

P Pozo-Rosich, KH Samaan, TJ Schwedt… - Advances in …, 2021 - Springer
Introduction The consistency of the treatment effect of galcanezumab throughout the dosing
interval is examined in patients with episodic and chronic migraine. Methods This study was …