Background: Glutathione system plays an important role in the protection of cells and tissue
against damage from oxidative stress. Impairment of the glutathione system due to genetic …

Glutathione S-transferase gene deletions are known detoxification agents and cause
oxidative damage. In different studies, variations in null allele frequency have been …

Objectives Clinical manifestations of sickle cell disease (SCD) result from sickling of Hb S
due to oxidation, which is augmented by accumulation of oxygen-free radicals. Deficiencies …

Sickle cell disease (SCD) complications are associated with oxidative stress. Glutathione S-
transferases (GSTs) are a group of enzymes that protect against oxidative stress. The aims …

Background: Sickle cell disease (SCD) is taken into account as one of the foremost types of
anemia in Sudan, particulary in the western part of the country. The glutathione system plays …

The hereditary deficiency of antioxidant enzymes when associated with sickle cell anemia
(SCA) further contributes to the oxidation of hemoglobin S, which increases the formation of …

Abstract Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most
common enzymopathy affecting millions of individuals worldwide. It is believed that the …

Objective Present study was undertaken to study the association between sickle cell anemia
(SCA) and glucose-6-phosphate dehydrogenase (G6PD) deficiency from Sahu and Kurmi …

Objectives To explore putative associations between specific variants in either the
glutathione S‐transferase (GST), haptoglobin (HP) or uridine 5′‐diphospho …

To find the influence of genetic polymorphisms of glutathione S-transferases M1 (GSTM1)
and T1 (GSTT1) on hematological parameters in smoker and non-smoker subjects, the …