BACKGROUND: Brain natriuretic peptide (BNP) has recently been shown to have a
cardioprotective effect in animal models of myocardial ischemia-reperfusion (IR) injury. We …

Background We have demonstrated that brain natriuretic peptide (BNP) is a cardiac
hormone predominantly synthesized in and secreted from the ventricle. We have also …

Background—Recent clinical trials have shown that systemic infusion of nesiritide, a
recombinant human brain natriuretic peptide (BNP), improves hemodynamic parameters in …

BACKGROUND: Previous studies have shown protective effects of brain natriuretic peptide
(BNP) against the postmyocardial infarction (MI) remodelling process. The transcription …

In this study, we employed rat model of acute myocardial necrosis induced by isoproterenol
(ISO) to study the possible roles of corin, the protease uniquely distributing in myocardium to …

The aim of this study was to detect early changes (within 1-4 h) in the brain natriuretic
peptide (BNP) levels of rats with acute myocardial infarction (AMI). A total of 35 Wistar rats …

The therapy for acute myocardial infarction (AMI) has been improved; yet, AMI remains a
major cause of death and heart failure in industrialized countries. B-type natriuretic peptide …

Natriuretic peptides are regulatory autacoids in the mammalian myocardium whose
functions, mediated via particulate guanylyl cyclase/cGMP, may include cytoprotection …

Inflammation plays a major role in the development of myocardial ischemia‐reperfusion (IR)
injury. Recombinant human brain natriuretic peptide (rhBNP), a man‐made version of a …

BACKGROUND: Brain natriuretic peptide is a marker of the severity of congestive heart
failure. However, the relation between its concentration and ventricular remodeling after …