Recent studies show that mitogen-activated protein kinases (MAPKs) and nuclear factor-
kappa B (NF-κB) signaling pathways are two pivotal roles contributing to the development of …

Acute lung injury (ALI) and its severe form, acute respiratory distress syndrome (ARDS),
pose a major clinical challenge. The major driving force in this syndrome is pulmonary …

Barbaloin is the major anthraquinone compound that is isolated from the leaf exudates of
Aloe vera and is often used as a bittering agent in alcoholic beverages. Here, we …

The aim of the present study was to explore the effect of naringenin on lipopolysaccharide
(LPS)‑induced acute lung injury (ALI) in a mouse model, as well as the underlying …

Acute lung injury (ALI) is a serious clinical syndrome with a high rate of mortality. The
activation of inflammation is well-recognized as a vital factor in the pathogenesis of …

The present study aimed to investigate the protective role of limonene in lipopolysaccharide
(LPS)-induced acute lung injury (ALI). ALI was induced in mice by intratracheal instillation of …

Phloretin, which can be isolated from apple trees, has demonstrable anti-inflammatory and
anti-oxidant effects in macrophages. We previously reported that phloretin could inhibit the …

The acute lung injury (ALI) is a leading cause of morbidity and mortality in critically ill
patients. Amygdalin is derived from the bitter apricot kernel, an efficacious Chinese herbal …

Acute lung injury (ALI), instilled by lipopolysaccharide (LPS), is a severe illness with
excessive mortality and has no specific treatment strategy. Luteolin is an anti‐inflammatory …

Shikonin, an analog of naphthoquinone pigments isolated from the root of Lithospermum
erythrorhyzon, was recently reported to exert beneficial anti-inflammatory effects both in vivo …