Uveal melanoma (UM) is one of the rare malignancies, which can be lethal despite local
treatment. Treatment options available now can control UM in early stages, but once it …

Background: Uveal melanoma (UM) is a rare subtype of melanoma that generally has a poor
prognosis once it has metastasized. Clinical trials evaluating immune checkpoint inhibitors …

Background: Uveal melanoma is the most common primary intraocular malignancy among
adults. It is, nevertheless, a rare disease, with an incidence of approximately one case per …

Uveal melanoma (UM) represents the most common intraocular malignancy in adults and
accounts for about 5% of all melanomas. Primary disease can be effectively controlled by …

Uveal melanoma (UM) is the most common intraocular malignancy in adults and shows a
high rate of metastatic spread. As randomized clinical trials with immune checkpoint …

Several studies have evaluated immune checkpoint inhibitors (ICIs) for metastatic uveal
melanoma; however, the efficacy of ICIs in the previous studies varied greatly. In this …

Background Uveal melanoma (UM) is highly refractory to treatment with dismal prognosis in
advanced stages. The value of the combined checkpoint blockade with CTLA-4 and PD-1 …

Uveal melanoma is the most prevalent primary intraocular tumour in adults with the
incidence between five and six cases per million people in the United States and Europe …

Uveal melanoma is an intraocular malignancy that, depending on its size and genetic make-
up, may lead to metastases in up to 50% of cases. Currently, no therapy has been proven to …

Background The use of immune checkpoint blockade (ICB) for uveal melanoma (UM) is little
established. The aim of this review was to provide a comprehensive overview on the …