Suppressed T cell-mediated immunity in patients with COVID-19: a clinical retrospective study in Wuhan, China

XU Bo, C Fan, A Wang, Y Zou, Y Yu, HE Cong, W Xia… - Journal of Infection, 2020 - Elsevier
Importance An ongoing outbreak of COVID-19 has exhibited significant threats around the
world. We found a significant decrease of T lymphocyte subsets and an increase of …

Dysregulation of immune response in patients with coronavirus 2019 (COVID-19) in Wuhan, China

C Qin, L Zhou, Z Hu, S Zhang, S Yang… - Clinical infectious …, 2020 - academic.oup.com
Abstract Background In December 2019, coronavirus 2019 (COVID-19) emerged in Wuhan
and rapidly spread throughout China. Methods Demographic and clinical data of all …

Reduction and functional exhaustion of T cells in patients with coronavirus disease 2019 (COVID-19)

B Diao, C Wang, Y Tan, X Chen, Y Liu, L Ning… - Frontiers in …, 2020 - frontiersin.org
Background: The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has posed great threat to human health …

Dynamic changes in lymphocyte subsets and parallel cytokine levels in patients with severe and critical COVID-19

Y Liu, W Tan, H Chen, Y Zhu, L Wan, K Jiang… - BMC infectious …, 2021 - Springer
Background The lack of knowledge regarding the pathogenesis and host immune response
during SARS-CoV-2 infection has limited the development of effective treatments. Thus, we …

[HTML][HTML] Aberrant hyperactivation of cytotoxic T-cell as a potential determinant of COVID-19 severity

CK Kang, GC Han, M Kim, G Kim, HM Shin… - International Journal of …, 2020 - Elsevier
Objectives We hypothesized that immune response may contribute to progression of
coronavirus disease-19 (COVID-19) at the second week of illness. Therefore, we compared …

Immune characteristics of severe and critical COVID-19 patients

L Yang, J Gou, J Gao, L Huang, Z Zhu, S Ji… - Signal transduction and …, 2020 - nature.com
Recently, the novel coronavirus disease (COVID-19) has broken out worldwide, 1 with rapid
increase of infected patients. COVID-19 dominantly leads to pneumonia. 2 Among these …

Clinical and immunological features of severe and moderate coronavirus disease 2019

G Chen, DI Wu, W Guo, Y Cao… - The Journal of …, 2020 - Am Soc Clin Investig
BACKGROUND Since December 2019, an outbreak of coronavirus disease 2019 (COVID-
19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in …

Epidemiological and clinical features of COVID-19 patients with and without pneumonia in Beijing, China

P Yang, Y Ding, Z Xu, R Pu, P Li, J Yan, J Liu, F Meng… - Medrxiv, 2020 - medrxiv.org
Abstract Background SARS-CoV-2-caused coronavirus disease (COVID-19) is posing a
large casualty. The features of COVID-19 patients with and without pneumonia, SARS-CoV …

[HTML][HTML] CD4+ T, CD8+ T counts and severe COVID-19: a meta-analysis

H Zhang, T Wu - The Journal of infection, 2020 - ncbi.nlm.nih.gov
We read an interesting study in your journal. A retrospective study by Liu et al. was
conducted to investigate the associated between lymphocyte subset counts and severe …

T cell response against SARS-CoV-2 persists after one year in patients surviving severe COVID-19

F Venet, M Gossez, F Bidar, M Bodinier… - …, 2022 - thelancet.com
Background In critically ill COVID-19 patients, the initial response to SARS-CoV-2 infection
is characterized by major immune dysfunctions. The capacity of these severe patients to …