Molecular mechanisms of human papillomavirus-induced carcinogenesis

M Lehoux, CM D'Abramo, J Archambault - Public health genomics, 2009 - karger.com
Approximately 20% of all cancers are associated with infectious agents. Among them,
human papillomaviruses (HPVs) are very common and are now recognized as the …

Molecular mechanisms underlying human papillomavirus E6 and E7 oncoprotein-induced cell transformation

S Mittal, L Banks - Mutation Research/Reviews in Mutation Research, 2017 - Elsevier
Human papillomaviruses (HPVs) are the causative agents of 5% of all human cancers, with
cervical cancer being the most important. Two viral oncoproteins, E6 and E7, are essential …

The human papillomavirus oncoproteins: a review of the host pathways targeted on the road to transformation

JA Scarth, MR Patterson… - Journal of General …, 2021 - microbiologyresearch.org
Persistent infection with high-risk human papillomaviruses (HR-HPVs) is the causal factor in
over 99% of cervical cancer cases, and a significant proportion of oropharyngeal and …

The human papillomavirus family and its role in carcinogenesis

M Tommasino - Seminars in cancer biology, 2014 - Elsevier
Human papillomaviruses (HPVs) are a family of small double-stranded DNA viruses that
have a tropism for the epithelia of the genital and upper respiratory tracts and for the skin …

High-risk human papillomaviral oncogenes E6 and E7 target key cellular pathways to achieve oncogenesis

NSL Yeo-Teh, Y Ito, S Jha - International journal of molecular sciences, 2018 - mdpi.com
Infection with high-risk human papillomavirus (HPV) has been linked to several human
cancers, the most prominent of which is cervical cancer. The integration of the viral genome …

[HTML][HTML] Human papillomaviruses in epigenetic regulations

J Durzynska, K Lesniewicz, E Poreba - Mutation Research/Reviews in …, 2017 - Elsevier
Abstract Human Papillomaviruses (HPVs) are double-stranded DNA viruses, that infect
epithelial cells and are etiologically involved in the development of human cancer. Today …

Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis

H Hausen - Journal of the National Cancer Institute, 2000 - academic.oup.com
During the past 20 years, several types of human papillomaviruses (HPVs) have been
identified that cause specific types of cancers. The etiology of cancer of the cervix has been …

Regulation of HPV transcription

AL Ribeiro, AS Caodaglio, L Sichero - Clinics, 2018 - SciELO Brasil
Human papillomavirus infection is associated with the development of malignant and benign
neoplasms. Approximately 40 viral types can infect the anogenital mucosa and are …

Human papillomavirus: E6 and E7 oncogenes

G Boulet, C Horvath, DV Broeck, S Sahebali… - The international journal …, 2007 - Elsevier
The recognition of a causal relationship between human papillomaviruses and cancer
almost 30 years ago led to a rapid expansion of knowledge in the field, resulting in the …

Molecular mechanisms of cervical carcinogenesis by high‐risk human papillomaviruses: novel functions of E6 and E7 oncoproteins

T Yugawa, T Kiyono - Reviews in medical virology, 2009 - Wiley Online Library
Over the last two decades, since the initial discovery of human papillomavirus (HPV) type 16
and 18 DNAs in cervical cancers by Dr. Harald zur Hausen (winner of the Nobel Prize in …