A concise and efficient total synthesis of the spermidine alkaloid (-)-isooncinotine
incorporating a 22-membered lactam ring is outlined. The approach is largely catalysis …

A 1, 2, 3, 4-tetrahydro-9a, 4a-(iminoethano)-9 H-carbazole (4) is a central structural feature
of the Strychnos alkaloid minfiensine (1) and akuammiline alkaloids such as vincorine (5) …

The macrocyclic spermidine alkaloid (−)-oncinotine (1), isolated from Oncinotis nitida
(Apocynaceae), was synthesized enantioselectively for the first time based on intramolecular …

Polycyclic alkaloids bearing all-carbon quaternary centers possess a diversity of biological
activities and are challenging targets in natural product synthesis. The development of a …

A concise and highly enantioselective total synthesis of the akuammiline alkaloid (−)-
vincorine has been accomplished. A key element of the synthesis is a stereoselective …

An enantioselective total synthesis of the Strychnos alkaloid (+)-minfiensine has been
accomplished. Prominent features of this synthesis include (i) a new enantioselective …

A catalytic asymmetric method for the chemical synthesis of alkaloids containing the 1, 2, 3,
4-tetrahydro-9a, 4a-(iminoethano)-9 H-carbazole (1) moiety is reported and verified by the …

An unprecedented asymmetric catalytic tandem aminolysis/aza-Michael addition reaction of
spirocyclic para-dienoneimides has been designed and developed through organocatalytic …

The first catalytic asymmetric total synthesis of the heptacyclic alkaloid (−)-communesin F is
described. A key step features an iridium-catalyzed asymmetric intermolecular cascade …

An efficient total synthesis of antibiotic (−)-codonopsinine 1 with an overall yield of 44% was
achieved from d-alanine as a chiral template. The key steps in our strategy are modified …