CXCR3, a double-edged sword in tumor progression and angiogenesis

C Billottet, C Quemener, A Bikfalvi - … et Biophysica Acta (BBA)-Reviews on …, 2013 - Elsevier
CXC chemokines are involved in chemotaxis, regulation of cell growth, induction of
apoptosis and modulation of angiostatic effects. CXCL9, CXCL10, CXCL11, CXCL4 and its …

[HTML][HTML] CXCL5: A coachman to drive cancer progression

J Deng, R Jiang, E Meng, H Wu - Frontiers in Oncology, 2022 - frontiersin.org
Chemokines are a class of pro-inflammatory cytokines that can recruit and activate
chemotactic cells. C‐X‐C motif chemokine ligand 5 (CXCL5) is a member of the chemokine …

Chemokine receptor trio: CXCR3, CXCR4 and CXCR7 crosstalk via CXCL11 and CXCL12

AK Singh, RK Arya, AK Trivedi, S Sanyal… - Cytokine & growth factor …, 2013 - Elsevier
Although chemokines are well established to function in immunity and endothelial cell
activation and proliferation, a rapidly growing literature suggests that CXC Chemokine …

[HTML][HTML] The CXCL8-CXCR1/2 pathways in cancer

Q Liu, A Li, Y Tian, JD Wu, Y Liu, T Li, Y Chen… - Cytokine & growth factor …, 2016 - Elsevier
Persistent infection or chronic inflammation contributes significantly to tumourigenesis and
tumour progression. CXC motif ligand 8 (CXCL8) is a chemokine that acts as an important …

The CC and CXC chemokines: major regulators of tumor progression and the tumor microenvironment

A Bikfalvi, C Billottet - American Journal of Physiology-Cell …, 2020 - journals.physiology.org
Chemokines are a family of soluble cytokines that act as chemoattractants to guide the
migration of cells, in particular of immune cells. However, chemokines are also involved in …

[HTML][HTML] The role of CXCR3 and its ligands in cancer

X Wang, Y Zhang, S Wang, H Ni, P Zhao… - Frontiers in …, 2022 - frontiersin.org
Chemokines are a class of small cytokines or signaling proteins that are secreted by cells.
Owing to their ability to induce directional chemotaxis of nearby responding cells, they are …

CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment

JA Burger, TJ Kipps - Blood, 2006 - ashpublications.org
Signals from the microenvironment have a profound influence on the maintenance and/or
progression of hematopoietic and epithelial cancers. Mesenchymal or marrow-derived …

CXCL11 promotes tumor progression by the biased use of the chemokine receptors CXCR3 and CXCR7

M Puchert, J Obst, C Koch, K Zieger, J Engele - Cytokine, 2020 - Elsevier
The chemokine, CXCL11, is highly expressed in different solid tumors and controls tumor
growth, metastasis, and lymphocyte infiltration. Although of potential clinical interest, it is …

[HTML][HTML] The emerging role of chemokine receptor CXCR2 in cancer progression

T Jaffer, D Ma - Translational Cancer Research, 2016 - tcr.amegroups.org
Chemokines and their receptors form a complex network controlling leukocyte migration,
particularly during infection and inflammation. Besides their critical contributions to the …

[HTML][HTML] CXCR2 receptor: regulation of expression, signal transduction, and involvement in cancer

J Korbecki, P Kupnicka, M Chlubek, J Gorący… - International Journal of …, 2022 - mdpi.com
Chemokines are a group of about 50 chemotactic cytokines crucial for the migration of
immune system cells and tumor cells, as well as for metastasis. One of the 20 chemokine …