Over the past three decades, significant progress has been made in the development of
potential regenerative cell-based therapies for neurodegenerative disease, with most …

Parkinson disease (PD) is characterized by loss of the A9 nigral neurons that provide
dopaminergic innervation to the striatum. This discovery led to the successful instigation of …

Current approaches to cell replacement therapy in Parkinson's disease are strongly focused
on the dopamine system, with the view that restoring dopaminergic inputs in a localized and …

✓ In this review, the authors discuss recent advances in the field of cell therapy for Parkinson
disease (PD). They compare and contrast recent clinical trials using fetal dopaminergic …

The development of a cell therapy for the neurodegenerative disorder Parkinson's disease is
a realistic ambition. It is pursued by researchers and companies alike, and spans different …

Upcoming clinical trials assessing transplantation of stem cell-derived dopaminergic
neurons into the striatum in patients with Parkinson's disease could generate …

Parkinson's disease is a common neurodegenerative disease with a lifetime incidence of
2.5% and a prevalence of at least 2% in individuals over 70 years old. Patients can be …

The ability to successfully replace lost nigral dopaminergic neurons in Parkinson's disease
(PD) has been clearly shown with fetal ventral mesencephalic transplants, albeit …

Recent news of an impending clinical cell transplantation trial in Parkinson's disease using
parthenogenetic stem cells as a source of donor tissue have raised hopes in the patient …

The aim of stem cell therapy for Parkinson's disease is to reconstruct nigro–striatal neuronal
pathways using endogenous neural stem/precursor cells or grafted dopaminergic neurons …