[HTML][HTML] Real-world use of nirmatrelvir-ritonavir in COVID-19 outpatients during BQ. 1, BQ. 1.1., and XBB. 1.5 predominant omicron variants in three US health systems …

NR Aggarwal, LE Beaty, TD Bennett… - The Lancet Regional …, 2024 - thelancet.com
Summary Background Ritonavir-boosted Nirmatrelvir (NMV-r), a protease inhibitor with in
vitro activity against SARS-CoV-2, can reduce risk of progression to severe COVID-19 …

Real-world use of nirmatrelvir-ritonavir in COVID-19 outpatients during the emergence of Omicron variants BA. 2/BA2. 12.1

NR Aggarwal, KC Molina, LE Beaty, TD Bennett… - Medrxiv, 2022 - medrxiv.org
ABSTRACT Background Ritonavir-boosted Nirmatrelvir (NMV-r), a protease inhibitor with in
vitro activity against SARS-CoV-2, has been shown to reduce risk of progression to severe …

[HTML][HTML] Real-world use of nirmatrelvir–ritonavir in outpatients with COVID-19 during the era of omicron variants including BA. 4 and BA. 5 in Colorado, USA: a …

NR Aggarwal, KC Molina, LE Beaty… - The Lancet Infectious …, 2023 - thelancet.com
Background Nirmatrelvir is a protease inhibitor with in-vitro activity against SARS-CoV-2,
and ritonavir-boosted nirmatrelvir can reduce the risk of progression to severe COVID-19 …

The effectiveness of novel oral antiviral treatment for non-hospitalized high-risk patients with COVID-19 during predominance of omicron XBB subvariants

CK Hsu, WH Hsu, BW Shiau, YW Tsai… - Expert Review of Anti …, 2024 - Taylor & Francis
Objectives This study investigated the association between nirmatrelvir plus ritonavir (NMV-
r) or molnupiravir and the outcomes of non-hospitalized high-risk patients with COVID-19 …

[HTML][HTML] Nirmatrelvir use and severe Covid-19 outcomes during the Omicron surge

R Arbel, Y Wolff Sagy, M Hoshen, E Battat… - … England Journal of …, 2022 - Mass Medical Soc
Background The oral protease inhibitor nirmatrelvir has shown substantial efficacy in high-
risk, unvaccinated patients infected with the B. 1.617. 2 (delta) variant of severe acute …

Nirmatrelvir or molnupiravir use and severe outcomes from omicron infections

DY Lin, F Abi Fadel, S Huang, AT Milinovich… - JAMA Network …, 2023 - jamanetwork.com
Importance Ritonavir-boosted nirmatrelvir and molnupiravir are currently used in the US and
in other countries to treat nonhospitalized patients who have mild-to-moderate COVID-19 …

Real-world effectiveness of nirmatrelvir/ritonavir use for COVID-19: A population-based cohort study in Ontario, Canada

KL Schwartz, J Wang, M Tadrous, BJ Langford… - medRxiv, 2022 - medrxiv.org
Background Our objective was to evaluate the real world effectiveness of
nirmatrelvir/ritonavir to prevent severe COVID-19 while Omicron and its subvariants …

[HTML][HTML] Population-based evaluation of the effectiveness of nirmatrelvir–ritonavir for reducing hospital admissions and mortality from COVID-19

KL Schwartz, J Wang, M Tadrous, BJ Langford… - Cmaj, 2023 - Can Med Assoc
Background: A randomized controlled trial involving a high-risk, unvaccinated population
that was conducted before the Omicron variant emerged found that nirmatrelvir–ritonavir …

Real-world effectiveness of molnupiravir and nirmatrelvir/ritonavir against mortality, hospitalization, and in-hospital outcomes among community-dwelling, ambulatory …

CKH Wong, ICH Au, KTK Lau, EHY Lau, BJ Cowling… - MedRxiv, 2022 - medrxiv.org
Background Evidence evaluating real-world effectiveness of oral antivirals against Omicron
variants is lacking. Methods An unselected, territory-wide cohort of all initially non …

[HTML][HTML] Real-world effectiveness of nirmatrelvir–ritonavir against BA. 4 and BA. 5 omicron SARS-CoV-2 variants

CKH Wong, KTK Lau, GM Leung - The Lancet Infectious Diseases, 2023 - thelancet.com
Over the past year of the COVID-19 pandemic, populations worldwide have been facing the
constant threat of the SARS-CoV-2 omicron variant and its sublineages, and the high …