Antimicrobial resistance threatens a resurgence of life-threatening bacterial infections and
the potential demise of many aspects of modern medicine. Despite intensive drug discovery …

New drug development strategies are needed to combat antimicrobial resistance. The object
of this perspective is to highlight one such strategy: treating infections with sets of drugs …

Resistance to antimicrobials and particularly multidrug resistance is one of the greatest
challenges in the health system nowadays. The continual increase in the rates of …

Introduction: In recent years, infections caused by multidrug-resistant bacterial pathogens
have become a huge issue to public healthcare systems. Indeed, the misuse of antibiotics …

The emerging and sustained resistance to antibiotics and the poor pipeline of new
antibacterials is creating a major health issue worldwide. Bacterial pathogens are …

Antimicrobial resistance has been a global health challenge that threatens our ability to
control and treat life-threatening bacterial infections. Despite ongoing efforts to identify new …

The increasing prevalence of infections caused by multidrug-resistant bacteria is a global
health problem that has been exacerbated by the dearth of novel classes of antibiotics …

Importance of the field: The emerging and sustained resistance to currently available
antibiotics and the poor pipeline of new antibacterials urgently call for the development of …

The introduction of effective antibacterial therapies for infectious diseases in the mid‐20th
century completely revolutionized clinical practices and helped to facilitate the development …

New antibiotics are necessary to treat microbial pathogens that are becoming increasingly
resistant to available treatment. Despite the medical need, the number of newly approved …