The m6A methyltransferase METTL3 promotes osteosarcoma progression by regulating the m6A level of LEF1

W Miao, J Chen, L Jia, J Ma, D Song - Biochemical and biophysical …, 2019 - Elsevier
Osteosarcoma (OS) is the most common and aggressive malignant bone sarcoma, which
occurs in rapidly growing bones in children and adolescents. However, the underlying …
被引用次数：115 相关文章 所有 6 个版本
[HTML] sciencedirect.com

[HTML][HTML] Silencing METTL3 inhibits the proliferation and invasion of osteosarcoma by regulating ATAD2

L Zhou, C Yang, N Zhang, X Zhang, T Zhao… - Biomedicine & …, 2020 - Elsevier
Background Osteosarcoma is the most common primary malignant bone tumor in children
and young adults. RNA N 6-methyladenosine (m 6 A) is the most abundant internal …
被引用次数：58 相关文章 所有 4 个版本
[PDF] europeanreview.org

[PDF][PDF] m6A methyltransferase METTL3 promotes the progression of prostate cancer via m6A-modified LEF1

XX Ma, ZG Cao, SL Zhao - Eur Rev Med Pharmacol Sci, 2020 - europeanreview.org
OBJECTIVE: This study aims to uncover the regulatory effects of METTL3 on promoting the
progression of prostate cancer (PCa) through N6-Methyladenosine (m6A) methylation on …
被引用次数：59 相关文章 所有 5 个版本
[PDF] tandfonline.com

RNA m6A Methyltransferase METTL3 Promotes The Growth Of Prostate Cancer By Regulating Hedgehog Pathway

J Cai, F Yang, H Zhan, J Situ, W Li, Y Mao… - OncoTargets and …, 2019 - Taylor & Francis
Purpose N6-methyladenosine (m6A) is the most abundant internal modification on
eukaryotic mRNA and gained increasing attention recently. More and more evidence …
被引用次数：125 相关文章 所有 9 个版本
[HTML] nih.gov

[HTML][HTML] N6-methyladenosine methyltransferase METTL3 promotes colorectal cancer cell proliferation through enhancing MYC expression

S Xiang, X Liang, S Yin, J Liu… - American journal of …, 2020 - ncbi.nlm.nih.gov
Abstract N6-methyladenosine (m6A) modification is the most common chemical modification
in eukaryotic mRNA, which plays a crucial role in regulating mRNA stability, splicing, and …
被引用次数：48 相关文章 所有 3 个版本
[PDF] tandfonline.com

m6A methyltransferase METTL3 suppresses colorectal cancer proliferation and migration through p38/ERK pathways

R Deng, Y Cheng, S Ye, J Zhang, R Huang… - OncoTargets and …, 2019 - Taylor & Francis
Purpose Although many biological processes are involved in the modification of N6-
methyladenosine (m6A), the exact role of m6A in the development of malignant tumors …
被引用次数：139 相关文章 所有 10 个版本
[HTML] nih.gov

[HTML][HTML] The M6A methyltransferase METTL3 promotes the development and progression of prostate carcinoma via mediating MYC methylation

Y Yuan, Y Du, L Wang, X Liu - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Abstract N6-methyladenosine (m 6 A) is the richest modification in mammalian messenger
RNAs (mRNAs), and exerts key roles in many biological processes, including cancer …
被引用次数：90 相关文章 所有 6 个版本
[HTML] cell.com

[HTML][HTML] METTL3 facilitates oral squamous cell carcinoma tumorigenesis by enhancing c-Myc stability via YTHDF1-mediated m6A modification

W Zhao, Y Cui, L Liu, X Ma, X Qi, Y Wang, Z Liu… - … Therapy-Nucleic Acids, 2020 - cell.com
N 6-Methyladenosine (m 6 A) is the most common internal modification of eukaryotic
messenger RNA (mRNA) that occurred on the N 6 nitrogen of adenosine. However, the roles …
被引用次数：144 相关文章 所有 6 个版本

The m6A methyltransferase METTL3 cooperates with demethylase ALKBH5 to regulate osteogenic differentiation through NF-κB signaling

J Yu, L Shen, Y Liu, H Ming, X Zhu, M Chu… - Molecular and cellular …, 2020 - Springer
As a m6A methylation modifier, METTL3 is functionally involved in various biological
processes. Nevertheless, the role of METTL3 in osteogenesis is not determined up to date …
被引用次数：81 相关文章 所有 6 个版本

N6-methyladenosine METTL3 promotes the breast cancer progression via targeting Bcl-2

H Wang, B Xu, J Shi - Gene, 2020 - Elsevier
Abstract N6-methyladenosine (m6A) is the most prevalent internal modification in
mammalian mRNAs and methyltransferase-like 3 (METTL3) is a vital methyltransferase in …
被引用次数：182 相关文章 所有 5 个版本