Do natural killer cells accelerate or prevent autoimmunity in multiple sclerosis?

JD Lünemann, C Münz - Brain, 2008 - academic.oup.com
In an attempt to identify biomarkers, which are able to better characterize the phenotypic
heterogeneity of multiple sclerosis, and at the same time dissect disease-relevant …

Enhancing natural killer cells is beneficial in multiple sclerosis–Yes

A Laroni - Multiple Sclerosis Journal, 2019 - journals.sagepub.com
A Laroni journals. sagepub. com/home/ms j 511 post-marketing experience revealed some
cases of severe brain inflammation with eosinophil infiltrates (Drug Reaction with …

Natural killer cells in multiple sclerosis: a review

M Mimpen, J Smolders, R Hupperts, J Damoiseaux - Immunology letters, 2020 - Elsevier
As the most common non-traumatic disabling disease among adolescents, multiple sclerosis
(MS) is a devastating neurological inflammatory disease of the central nervous system …

The role of natural killer cells in multiple sclerosis and their therapeutic implications

C Chanvillard, RF Jacolik, C Infante-Duarte… - Frontiers in …, 2013 - frontiersin.org
Multiple sclerosis (MS) is assumed to be an autoimmune disease initiated by autoreactive T
cells that recognize central nervous system antigens. Although adaptive immunity is clearly …

Role of natural killer cells in the pathogenesis and progression of multiple sclerosis

B Morandi, P Bramanti, I Bonaccorsi, E Montalto… - Pharmacological …, 2008 - Elsevier
Natural killer (NK) cells are a subset of lymphocytes which have long been alleged to play
an immunoregulatory role in the prevention of autoimmune diseases. Here, we briefly review …

Enhancing natural killer cells is beneficial in multiple sclerosis–No

Q Liu, FD Shi - Multiple Sclerosis Journal, 2019 - journals.sagepub.com
Natural killer (NK) cells are large, granular lymphocytes that represent a key component of
the innate immune system. NK cells act as an early responder of the immune system to …

Role of natural killer cells in multiple sclerosis

AA Maghazachi - International Scholarly Research Notices, 2012 - Wiley Online Library
Although the etiology of multiple sclerosis (MS) is not known, the consensus is that Th1 cells
sensitized to myelin proteins in the periphery are recruited into the CNS and damage the …

The regulatory role of natural killer cells in multiple sclerosis

K Takahashi, T Aranami, M Endoh, S Miyake… - Brain, 2004 - academic.oup.com
Multiple sclerosis is a chronic demyelinating disease of presumed autoimmune
pathogenesis. The patients with multiple sclerosis typically shows alternating relapse and …

Natural killer cell subsets in cerebrospinal fluid of patients with multiple sclerosis

E Rodríguez-Martín, C Picón… - Clinical & …, 2015 - academic.oup.com
Changes in blood natural killer (NK) cells, important players of the immune innate system,
have been described in multiple sclerosis (MS). We studied percentages and total cell …

Interleukin‐2/interleukin‐2 antibody therapy induces target organ natural killer cells that inhibit central nervous system inflammation

J Hao, D Campagnolo, R Liu, W Piao, S Shi… - Annals of …, 2011 - Wiley Online Library
Objective: The role of natural killer (NK) cells in regulating multiple sclerosis (MS) is not well
understood. Additional studies with NK cells might provide insight into the mechanism of …