Radical cyclization cascades triggered by a trifluoromethyl radical represent a valuable tool
for accessing highly complex and biologically relevant scaffolds. Herein, we introduce a …

A de novo method for direct construction of cyclopenta [b] indolines via a photocatalytic
fluoroalkylative radical cyclization cascade of ynamides has been established, which …

Multicomponent reactions (MCRs) have demonstrated enormous potential in the direct and
single-step synthesis of chemical entities with structural diversity. However, the …

Nitrogen-containing heterocycles are prevalent in both natural and synthetic bioactive
molecules. We report herein an unprecedented protocol for the radical …

A mild and metal-free protocol for visible-light induced intramolecular radical cyclization of N-
allyl (propargyl)-2-bromo-2, 2-difluoro-N-arylacetamide has been developed. This strategy …

In this paper, a series of diverse alkenes were engaged in radical tandem cyclization
initiated by a CF2 radical precursor via photoredox catalysis, affording various cyclic gem …

Traditional methods for the transformation of N-allyl ynamides rely on the formation of a
ketenimine intermediate or its equivalent, while novel reaction modes remain to be …

Monofluoromethylated compounds exhibit unique physicochemical properties with wide
applications in drug discovery. The direct monofluoromethylation of common feedstocks …

Access to cyclic gem -difluoroacyl scaffolds via electrochemical and visible light photocatalytic
radical tandem cyclization of heteroaryl chlorodiflu ... - Chemical Communications (RSC …

Photoredox-catalyzed aminoarylation and thioamination of unactivated alkenes have been
developed, providing novel synthetic routes to access synthetically challenging quaternary …