Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection
Middle East respiratory syndrome coronavirus (MERS-CoV) continues to cause outbreaks in
humans as a result of spillover events from dromedaries. In contrast to humans, MERS-CoV …
humans as a result of spillover events from dromedaries. In contrast to humans, MERS-CoV …
Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus
Middle East Respiratory Syndrome (MERS) is a highly lethal pulmonary infection caused by
a previously unidentified coronavirus (CoV), likely transmitted to humans by infected camels …
a previously unidentified coronavirus (CoV), likely transmitted to humans by infected camels …
Importance of neutralizing monoclonal antibodies targeting multiple antigenic sites on the Middle East respiratory syndrome coronavirus spike glycoprotein to avoid …
Middle East respiratory syndrome coronavirus (MERS-CoV) causes a highly lethal
pulmonary infection with∼ 35% mortality. The potential for a future pandemic originating …
pulmonary infection with∼ 35% mortality. The potential for a future pandemic originating …
Recombinant receptor-binding domains of multiple Middle East respiratory syndrome coronaviruses (MERS-CoVs) induce cross-neutralizing antibodies against …
W Tai, Y Wang, CA Fett, G Zhao, F Li… - Journal of …, 2017 - Am Soc Microbiol
Middle East respiratory syndrome coronavirus (MERS-CoV) binds to cellular receptor
dipeptidyl peptidase 4 (DPP4) via the spike (S) protein receptor-binding domain (RBD). The …
dipeptidyl peptidase 4 (DPP4) via the spike (S) protein receptor-binding domain (RBD). The …
[HTML][HTML] A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein
Y Li, Y Wan, P Liu, J Zhao, G Lu, J Qi, Q Wang, X Lu… - Cell research, 2015 - nature.com
Abstract The newly-emerging Middle East respiratory syndrome coronavirus (MERS-CoV)
can cause severe and fatal acute respiratory disease in humans. Despite global efforts, the …
can cause severe and fatal acute respiratory disease in humans. Despite global efforts, the …
Exceptionally potent neutralization of Middle East respiratory syndrome coronavirus by human monoclonal antibodies
T Ying, L Du, TW Ju, P Prabakaran, CCY Lau… - Journal of …, 2014 - Am Soc Microbiol
ABSTRACT The recently discovered Middle East respiratory syndrome coronavirus (MERS-
CoV) continues to infect humans, with high mortality. Specific, highly effective therapeutics …
CoV) continues to infect humans, with high mortality. Specific, highly effective therapeutics …
[HTML][HTML] Passive transfer of a germline-like neutralizing human monoclonal antibody protects transgenic mice against lethal Middle East respiratory syndrome …
AS Agrawal, T Ying, X Tao, T Garron, A Algaissi… - Scientific reports, 2016 - nature.com
Abstract Middle East Respiratory Syndrome coronavirus (MERS-CoV) has repeatedly
caused outbreaks in the Arabian Peninsula. To date, no approved medical countermeasures …
caused outbreaks in the Arabian Peninsula. To date, no approved medical countermeasures …
[HTML][HTML] Enhanced ability of oligomeric nanobodies targeting MERS coronavirus receptor-binding domain
L He, W Tai, J Li, Y Chen, Y Gao, J Li, S Sun, Y Zhou… - Viruses, 2019 - mdpi.com
Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV), an infectious
coronavirus first reported in 2012, has a mortality rate greater than 35%. Therapeutic …
coronavirus first reported in 2012, has a mortality rate greater than 35%. Therapeutic …
Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution
XC Tang, SS Agnihothram, Y Jiao… - Proceedings of the …, 2014 - National Acad Sciences
The newly emerging Middle East Respiratory Syndrome coronavirus (MERS-CoV) causes a
Severe Acute Respiratory Syndrome-like disease with∼ 43% mortality. Given the recent …
Severe Acute Respiratory Syndrome-like disease with∼ 43% mortality. Given the recent …
A conformation-dependent neutralizing monoclonal antibody specifically targeting receptor-binding domain in Middle East respiratory syndrome coronavirus spike …
L Du, G Zhao, Y Yang, H Qiu, L Wang, Z Kou… - Journal of …, 2014 - Am Soc Microbiol
Prophylactic and therapeutic strategies are urgently needed to combat infections caused by
the newly emerged Middle East respiratory syndrome coronavirus (MERS-CoV). Here, we …
the newly emerged Middle East respiratory syndrome coronavirus (MERS-CoV). Here, we …