Application of nanopore sequencing technology in the clinical diagnosis of infectious diseases

LL Zhang, C Zhang, JP Peng - Biomedical and Environmental Sciences, 2022 - Elsevier
Infectious diseases are an enormous public health burden and a growing threat to human
health worldwide. Emerging or classic recurrent pathogens, or pathogens with resistant …

The applications of nanopore sequencing technology in pathogenic microorganism detection

X Zhu, S Yan, F Yuan, S Wan - Canadian Journal of Infectious …, 2020 - Wiley Online Library
Infectious diseases are major threats to human health and lead to a serious public health
burden. The emergence of new pathogens and the mutation of known pathogens challenge …

Third-generation sequencing in the clinical laboratory: exploring the advantages and challenges of nanopore sequencing

LM Petersen, IW Martin, WE Moschetti… - Journal of clinical …, 2019 - Am Soc Microbiol
Metagenomic sequencing for infectious disease diagnostics is an important tool that holds
promise for use in the clinical laboratory. Challenges for implementation so far include high …

Application of Nanopore sequencing in the diagnosis and treatment of pulmonary infections

J Chen, F Xu - Molecular Diagnosis & Therapy, 2023 - Springer
This review provides an in-depth discussion of the development, principles and utility of
nanopore sequencing technology and its diverse applications in the identification of various …

Nanopore sequencing: a rapid solution for infectious disease epidemics

Y Cao, J Li, X Chu, H Liu, W Liu, D Liu - Science China Life Sciences, 2019 - Springer
Emerging and re-emerging infectious diseases have given rise to a large number of human
infections, morbidity, and heavy economic burden, including the Middle East respiratory …

Portable nanopore-sequencing technology: Trends in development and applications

P Chen, Z Sun, J Wang, X Liu, Y Bai, J Chen… - Frontiers in …, 2023 - frontiersin.org
Sequencing technology is the most commonly used technology in molecular biology
research and an essential pillar for the development and applications of molecular biology …

Oxford nanopore sequencing in clinical microbiology and infection diagnostics

D Sheka, N Alabi, PMK Gordon - Briefings in bioinformatics, 2021 - academic.oup.com
Extended turnaround times and large economic costs hinder the usage of currently applied
screening methods for bacterial pathogen identification (ID) and antimicrobial susceptibility …

Clinical performance of nanopore targeted sequencing for diagnosing infectious diseases

Y Fu, Q Chen, M Xiong, J Zhao, S Shen… - Microbiology …, 2022 - Am Soc Microbiol
The gold standard for confirming bacterial infections is culture-positive, which has a long
sample-to-result turnaround time and poor sensitivity for unculturable and fastidious …

Nanopore-targeted sequencing improves the diagnosis and treatment of patients with serious infections

Y Zhang, X Lu, LV Tang, L Xia, Y Hu - MBio, 2023 - Am Soc Microbiol
Serious infections are characterized by rapid progression, poor prognosis, and difficulty in
diagnosis. Recently, a new technique known as nanopore-targeted sequencing (NTS) was …

Nanopore sequencing technology and its applications

P Zheng, C Zhou, Y Ding, B Liu, L Lu, F Zhu… - MedComm, 2023 - Wiley Online Library
Since the development of Sanger sequencing in 1977, sequencing technology has played a
pivotal role in molecular biology research by enabling the interpretation of biological genetic …