The origin and evolution of cell types has emerged as a key topic in evolutionary biology.
Driven by rapidly accumulating single-cell datasets, recent attempts to infer cell type …

Motivation: Animals build their bodies by altering the fates of cells. The way in which they do
so is reflected in the topology of cell lineages and the fates of terminal cells. Cell lineages …

Lineage tracing and fate mapping, overlapping yet distinct disciplines to follow cells and
their progeny, have evolved rapidly over the last century. Lineage tracing aims to identify all …

Natural and induced somatic mutations that accumulate in the genome during development
record the phylogenetic relationships of cells; however, whether these lineage barcodes can …

The concept of cell fate relates to the future identity of a cell, and its daughters, which is
obtained via cell differentiation and division. Understanding, predicting, and manipulating …

How astounding neuronal diversity arises from variable cell lineages in vertebrates remains
mostly elusive. By in vivo lineage tracing of∼ 1,000 single zebrafish retinal progenitors, we …

INTRODUCTION Metazoan development represents a big jump in complexity compared
with unicellular life in two aspects: cell-type differentiation and cell spatial organization. In …

Early retinal progenitor cells (RPCs) in vertebrates produce lineages that vary greatly both in
terms of cell number and fate composition, yet how this variability is achieved remains …

Objectives: The analysis of individual cell fates within a population of stem and progenitor
cells is still a major experimental challenge in stem cell biology. However, new monitoring …

Cellular differentiation is a common underlying feature of all multicellular organisms through
which naïve cells progressively become fate restricted and develop into mature cells with …