Increased prevalence of Alzheimer's disease‐like β‐amyloid deposits in the neuropil and
within neurons occurs in the brains of non‐demented individuals with heart disease. Heart …

Pioneering autopsy studies revealed a possible link between coronary artery disease,
cholesterol and Alzheimer's disease (AD). In the cholesterol-fed rabbit model of human …

Clinical, epidemiological, and laboratory studies suggest that cholesterol may play a role in
the pathogenesis of Alzheimer's disease (AD). Transgenic mice exhibiting an Alzheimer's β …

Increased circulating cholesterol has been long linked to an increased risk of coronary artery
disease (CAD), and is now linked to an increased risk of developing Alzheimer s disease …

This report presents the scientific rationale and hypothesis for the investigator‐initiated,
double‐blind, placebo‐controlled Alzheimer's Disease Cholesterol‐Lowering Treatment …

Epidemiological, animal, and cellular studies suggest that abnormalities in cholesterol
metabolism are important in the pathogenesis of Alzheimer's disease (AD), potentially by …

Accumulation of a 40–42-amino acid peptide, termed amyloid-β peptide (Aβ), is associated
with Alzheimer's disease (AD), and identifying medicines that inhibit Aβ could help patients …

Abstract β-amyloid and ALZ-50 immunocytochemical reactivity were determined in the
brains of rabbits fed either a control or 2% cholesterol diet. Control rabbits demonstrated no …

Fundamental questions on the pathogenesis of Alzheimer's disease (AD) are how nontoxic,
soluble amyloid β‐protein (Aβ) is converted to its toxic, aggregated form and how functional …

Increased circulating cholesterol is known to promote risk of coronary artery disease. It is
now emerging that cholesterol promotes production and accumulation of amyloid β (Aβ) …