Neuroinflammation is a specific or nonspecific immunological reaction in the central nervous
system that is induced by microglia activation. Appropriate regulation of activated microglial …

Glial activation and neuroinflammation play significant roles in apoptosis as well as in the
development of cognitive and memory deficits. Neuroinflammation is also a critical feature in …

Abstract Hyperoside (quercetin-3-O-β-d-galactoside) is an active compound isolated from
herbs. Neuroinflammation is a key mechanism involved in neurodegenerative disorders …

Microglia play an important role in the immune defense in the central nervous system.
Activation of microglia leads to the production of excessive inflammatory molecules and …

Tangeretin, a flavonoid from citrus fruit peels, has been proven to play an important role in
anti-inflammatory responses and neuroprotective effects in several disease models, but …

Hesperetin is a bioactive flavonoid in the body, produced from hesperidin. No
comprehensive studies have shown its protective effects in neurodegenerative disorders …

Microglial activation elicits an immune response by producing proinflammatory modulators
and cytokines that cause neurodegeneration. Therefore, a plausible strategy to prevent …

Accumulating evidence suggests that neuroinflammation is closely associated with the
pathogenesis of neurodegenerative disorders such as Parkinson's disease and Alzheimer's …

Naringenin, one of the most abundant flavonoids in citrus fruits and grapefruits, has been
reported to exhibit anti-inflammatory and antitumor activities. However, the cellular and …

Neurodegenerative disease is a disease state in which neurons in the spinal cord and brain
are lost. Studies show that sustained neuroinflammatory reactions release toxic factors …